Porcine dermis implants in soft-tissue reconstruction: current status

Neil J Smart,1 Nicholas Bryan,2 John A Hunt,2 Ian R Daniels1 1Exeter Surgical Health Services Research Unit, Royal Devon and Exeter Hospital, Exeter, UK; 2Clinical Engineering (UKCTE), The Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK Abstract: Soft-tissue reconst...

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Autores principales:	Smart NJ, Bryan N, Hunt JA, Daniels IR
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f7b4c79653864c99af372ecb8778c1ea
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spelling	oai:doaj.org-article:f7b4c79653864c99af372ecb8778c1ea2021-12-02T07:12:12ZPorcine dermis implants in soft-tissue reconstruction: current status1177-5475https://doaj.org/article/f7b4c79653864c99af372ecb8778c1ea2014-03-01T00:00:00Zhttp://www.dovepress.com/porcine-dermis-implants-in-soft-tissue-reconstruction-current-status-a16046https://doaj.org/toc/1177-5475 Neil J Smart,1 Nicholas Bryan,2 John A Hunt,2 Ian R Daniels1 1Exeter Surgical Health Services Research Unit, Royal Devon and Exeter Hospital, Exeter, UK; 2Clinical Engineering (UKCTE), The Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK Abstract: Soft-tissue reconstruction for a variety of surgical conditions, such as abdominal wall hernia or pelvic organ prolapse, remains a challenge. There are numerous meshes available that may be simply categorized as either synthetic or biologic. Within biologic meshes, porcine dermal meshes have come to dominate the market. This review examines the current evidence for their use and the limitations of knowledge. Although there is increasing evidence to support their safety, long-term follow-up studies that support their efficacy are lacking. Numerous clinical trials that remain ongoing may help elucidate their precise role in soft-tissue reconstruction. Keywords: hernia, mesh, xenograft, biologicSmart NJBryan NHunt JADaniels IRDove Medical PressarticleMedicine (General)R5-920ENBiologics: Targets & Therapy, Vol 2014, Iss default, Pp 83-90 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Smart NJ Bryan N Hunt JA Daniels IR Porcine dermis implants in soft-tissue reconstruction: current status
description	Neil J Smart,1 Nicholas Bryan,2 John A Hunt,2 Ian R Daniels1 1Exeter Surgical Health Services Research Unit, Royal Devon and Exeter Hospital, Exeter, UK; 2Clinical Engineering (UKCTE), The Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK Abstract: Soft-tissue reconstruction for a variety of surgical conditions, such as abdominal wall hernia or pelvic organ prolapse, remains a challenge. There are numerous meshes available that may be simply categorized as either synthetic or biologic. Within biologic meshes, porcine dermal meshes have come to dominate the market. This review examines the current evidence for their use and the limitations of knowledge. Although there is increasing evidence to support their safety, long-term follow-up studies that support their efficacy are lacking. Numerous clinical trials that remain ongoing may help elucidate their precise role in soft-tissue reconstruction. Keywords: hernia, mesh, xenograft, biologic
format	article
author	Smart NJ Bryan N Hunt JA Daniels IR
author_facet	Smart NJ Bryan N Hunt JA Daniels IR
author_sort	Smart NJ
title	Porcine dermis implants in soft-tissue reconstruction: current status
title_short	Porcine dermis implants in soft-tissue reconstruction: current status
title_full	Porcine dermis implants in soft-tissue reconstruction: current status
title_fullStr	Porcine dermis implants in soft-tissue reconstruction: current status
title_full_unstemmed	Porcine dermis implants in soft-tissue reconstruction: current status
title_sort	porcine dermis implants in soft-tissue reconstruction: current status
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/f7b4c79653864c99af372ecb8778c1ea
work_keys_str_mv	AT smartnj porcinedermisimplantsinsofttissuereconstructioncurrentstatus AT bryann porcinedermisimplantsinsofttissuereconstructioncurrentstatus AT huntja porcinedermisimplantsinsofttissuereconstructioncurrentstatus AT danielsir porcinedermisimplantsinsofttissuereconstructioncurrentstatus
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Porcine dermis implants in soft-tissue reconstruction: current status

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