Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease.
<h4>Background and aim</h4>Alcohol-related liver disease (ALD) remains a leading cause of liver-related morbidity and mortality. Age, fibrosis stage, MELD score and continued alcohol consumption predict outcome in everyday clinical practice. In previous studies increased hepatocyte nucle...
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Main Authors: | Aloysious Aravinthan, Giada Pietrosi, Matthew Hoare, James Jupp, Aileen Marshall, Clare Verrill, Susan Davies, Adrian Bateman, Nick Sheron, Michael Allison, Graeme J M Alexander |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/f7baa89d77754508aaf5a78aa3fd829b |
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