The anti-viral dynamin family member MxB participates in mitochondrial integrity

Mx proteins belong to the dynamin family of large GTPases and are highly induced by interferon in virally infected cells. The authors show that uninfected immune cells and hepatocytes also express MxB protein that associates with mitochondria to alter the morphology and genome of this organelle.

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Autores principales:	Hong Cao, E. W. Krueger, Jing Chen, Kristina Drizyte-Miller, Mary E. Schulz, Mark A. McNiven
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f7bc8160d7f84107957d916022d0b4ee
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spelling	oai:doaj.org-article:f7bc8160d7f84107957d916022d0b4ee2021-12-02T14:42:46ZThe anti-viral dynamin family member MxB participates in mitochondrial integrity10.1038/s41467-020-14727-w2041-1723https://doaj.org/article/f7bc8160d7f84107957d916022d0b4ee2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14727-whttps://doaj.org/toc/2041-1723Mx proteins belong to the dynamin family of large GTPases and are highly induced by interferon in virally infected cells. The authors show that uninfected immune cells and hepatocytes also express MxB protein that associates with mitochondria to alter the morphology and genome of this organelle.Hong CaoE. W. KruegerJing ChenKristina Drizyte-MillerMary E. SchulzMark A. McNivenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hong Cao E. W. Krueger Jing Chen Kristina Drizyte-Miller Mary E. Schulz Mark A. McNiven The anti-viral dynamin family member MxB participates in mitochondrial integrity
description	Mx proteins belong to the dynamin family of large GTPases and are highly induced by interferon in virally infected cells. The authors show that uninfected immune cells and hepatocytes also express MxB protein that associates with mitochondria to alter the morphology and genome of this organelle.
format	article
author	Hong Cao E. W. Krueger Jing Chen Kristina Drizyte-Miller Mary E. Schulz Mark A. McNiven
author_facet	Hong Cao E. W. Krueger Jing Chen Kristina Drizyte-Miller Mary E. Schulz Mark A. McNiven
author_sort	Hong Cao
title	The anti-viral dynamin family member MxB participates in mitochondrial integrity
title_short	The anti-viral dynamin family member MxB participates in mitochondrial integrity
title_full	The anti-viral dynamin family member MxB participates in mitochondrial integrity
title_fullStr	The anti-viral dynamin family member MxB participates in mitochondrial integrity
title_full_unstemmed	The anti-viral dynamin family member MxB participates in mitochondrial integrity
title_sort	anti-viral dynamin family member mxb participates in mitochondrial integrity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f7bc8160d7f84107957d916022d0b4ee
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The anti-viral dynamin family member MxB participates in mitochondrial integrity

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