Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss

Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss

Abstract Regulators of G protein signaling (RGS) accelerate the GTPase activity of G proteins to enable rapid termination of the signals triggered by G protein-coupled receptors (GPCRs). Activation of several GPCRs, including cannabinoid receptor 2 (CB2R) and adenosine A1 receptor (A1AR), protects a...

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Autores principales: Asmita Dhukhwa, Raheem F. H. Al Aameri, Sandeep Sheth, Debashree Mukherjea, Leonard Rybak, Vickram Ramkumar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/f7bd4bab02fb490bac2efed2eca9e9b6
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