Individual variations in ‘brain age’ relate to early-life factors more than to longitudinal brain change

Brain age is a widely used index for quantifying individuals’ brain health as deviation from a normative brain aging trajectory. Higher-than-expected brain age is thought partially to reflect above-average rate of brain aging. Here, we explicitly tested this assumption in two independent large test...

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Bibliographic Details
Main Authors:	Didac Vidal-Pineiro, Yunpeng Wang, Stine K Krogsrud, Inge K Amlien, William FC Baaré, David Bartres-Faz, Lars Bertram, Andreas M Brandmaier, Christian A Drevon, Sandra Düzel, Klaus Ebmeier, Richard N Henson, Carme Junqué, Rogier Andrew Kievit, Simone Kühn, Esten Leonardsen, Ulman Lindenberger, Kathrine S Madsen, Fredrik Magnussen, Athanasia Monika Mowinckel, Lars Nyberg, James M Roe, Barbara Segura, Stephen M Smith, Øystein Sørensen, Sana Suri, Rene Westerhausen, Andrew Zalesky, Enikő Zsoldos, Kristine Beate Walhovd, Anders Fjell
Format:	article
Language:	EN
Published:	eLife Sciences Publications Ltd 2021
Subjects:	Aging brain age gap Brain age delta brain decline neuroimaging T1w Medicine R Science Q Biology (General) QH301-705.5
Online Access:	https://doaj.org/article/f7bfb3e601d344e5b6d9bf1556cfb70a
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Individual variations in ‘brain age’ relate to early-life factors more than to longitudinal brain change

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