mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?

ABSTRACT Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how “Adenosine A2B receptor deficiency promotes host defenses against Gram-negative bacterial pneumonia” by Barletta et al. (K. E. Barlett...

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Main Author:	Elsa N. Bou Ghanem
Format:	article
Language:	EN
Published:	American Society for Microbiology 2019
Subjects:	CD73 Streptococcus pneumoniae bacterial pneumonia extracellular adenosine inflammation lung infection Microbiology QR1-502
Online Access:	https://doaj.org/article/f7d5e8f1dd294228816eb080a5d97c24
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spelling	oai:doaj.org-article:f7d5e8f1dd294228816eb080a5d97c242021-11-15T15:22:27ZmSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?10.1128/mSphere.00326-192379-5042https://doaj.org/article/f7d5e8f1dd294228816eb080a5d97c242019-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00326-19https://doaj.org/toc/2379-5042ABSTRACT Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how “Adenosine A2B receptor deficiency promotes host defenses against Gram-negative bacterial pneumonia” by Barletta et al. (K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044–1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC) impacted her own work examining the role of the extracellular adenosine pathway in neutrophil responses and host defense against pneumococcal pneumonia.Elsa N. Bou GhanemAmerican Society for MicrobiologyarticleCD73Streptococcus pneumoniaebacterial pneumoniaextracellular adenosineinflammationlung infectionMicrobiologyQR1-502ENmSphere, Vol 4, Iss 4 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	CD73 Streptococcus pneumoniae bacterial pneumonia extracellular adenosine inflammation lung infection Microbiology QR1-502
spellingShingle	CD73 Streptococcus pneumoniae bacterial pneumonia extracellular adenosine inflammation lung infection Microbiology QR1-502 Elsa N. Bou Ghanem mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?
description	ABSTRACT Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how “Adenosine A2B receptor deficiency promotes host defenses against Gram-negative bacterial pneumonia” by Barletta et al. (K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044–1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC) impacted her own work examining the role of the extracellular adenosine pathway in neutrophil responses and host defense against pneumococcal pneumonia.
format	article
author	Elsa N. Bou Ghanem
author_facet	Elsa N. Bou Ghanem
author_sort	Elsa N. Bou Ghanem
title	mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?
title_short	mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?
title_full	mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?
title_fullStr	mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?
title_full_unstemmed	mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?
title_sort	msphere of influence: adenosine in host defense against bacterial pneumonia—friend or foe?
publisher	American Society for Microbiology
publishDate	2019
url	https://doaj.org/article/f7d5e8f1dd294228816eb080a5d97c24
work_keys_str_mv	AT elsanboughanem msphereofinfluenceadenosineinhostdefenseagainstbacterialpneumoniafriendorfoe
_version_	1718427986357649408

mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia—Friend or Foe?

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