Is obesity in women protective against osteoporosis?

Is obesity in women protective against osteoporosis?

Silvia Migliaccio1,2, Emanuela A Greco1, Rachele Fornari1, Lorenzo M Donini1, Andrea Lenzi11Dipartimento di Medicina Sperimentale, Sezione di Fisiopatologia, Endocrinologia e Nutrizione, Università Sapienza di Roma, 2Dipartimento di Scienze della Salute, Università Foro...

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Autores principales: Migliaccio S, Greco EA, Fornari R, Donini LM, Lenzi A
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2011
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Specialties of internal medicine
RC581-951
Acceso en línea:https://doaj.org/article/f7dcc275f43442e889b67675c956ac94
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spelling oai:doaj.org-article:f7dcc275f43442e889b67675c956ac942021-12-02T11:34:14ZIs obesity in women protective against osteoporosis?1178-7007https://doaj.org/article/f7dcc275f43442e889b67675c956ac942011-07-01T00:00:00Zhttp://www.dovepress.com/is-obesity-in-women-protective-against-osteoporosis-a7791https://doaj.org/toc/1178-7007Silvia Migliaccio1,2, Emanuela A Greco1, Rachele Fornari1, Lorenzo M Donini1, Andrea Lenzi11Dipartimento di Medicina Sperimentale, Sezione di Fisiopatologia, Endocrinologia e Nutrizione, Università Sapienza di Roma, 2Dipartimento di Scienze della Salute, Università Foro Italico di Roma, ItaliaAbstract: The belief that obesity is protective against osteoporosis has recently come into question. The latest epidemiologic and clinical studies have shown that a high level of fat mass might be a risk factor for osteoporosis and fragility fractures. Further, increasing evidence seems to indicate that different components of the metabolic syndrome, ie, hypertension, increased triglycerides, reduced high-density lipoprotein cholesterol, are also potential risk factors for the development of low bone mineral density and osteoporosis. This review considers both the older and more recent data in the literature in order to evaluate further the relationship between fat tissue and bone tissue.Keywords: bone mineral density, fat mass, body mass index, fractures, adipocytesMigliaccio SGreco EAFornari RDonini LMLenzi ADove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2011, Iss default, Pp 273-282 (2011)
institution DOAJ
collection DOAJ
language EN
topic Specialties of internal medicine
RC581-951
spellingShingle Specialties of internal medicine
RC581-951
Migliaccio S
Greco EA
Fornari R
Donini LM
Lenzi A
Is obesity in women protective against osteoporosis?
description Silvia Migliaccio1,2, Emanuela A Greco1, Rachele Fornari1, Lorenzo M Donini1, Andrea Lenzi11Dipartimento di Medicina Sperimentale, Sezione di Fisiopatologia, Endocrinologia e Nutrizione, Università Sapienza di Roma, 2Dipartimento di Scienze della Salute, Università Foro Italico di Roma, ItaliaAbstract: The belief that obesity is protective against osteoporosis has recently come into question. The latest epidemiologic and clinical studies have shown that a high level of fat mass might be a risk factor for osteoporosis and fragility fractures. Further, increasing evidence seems to indicate that different components of the metabolic syndrome, ie, hypertension, increased triglycerides, reduced high-density lipoprotein cholesterol, are also potential risk factors for the development of low bone mineral density and osteoporosis. This review considers both the older and more recent data in the literature in order to evaluate further the relationship between fat tissue and bone tissue.Keywords: bone mineral density, fat mass, body mass index, fractures, adipocytes
format article
author Migliaccio S
Greco EA
Fornari R
Donini LM
Lenzi A
author_facet Migliaccio S
Greco EA
Fornari R
Donini LM
Lenzi A
author_sort Migliaccio S
title Is obesity in women protective against osteoporosis?
title_short Is obesity in women protective against osteoporosis?
title_full Is obesity in women protective against osteoporosis?
title_fullStr Is obesity in women protective against osteoporosis?
title_full_unstemmed Is obesity in women protective against osteoporosis?
title_sort is obesity in women protective against osteoporosis?
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/f7dcc275f43442e889b67675c956ac94
work_keys_str_mv AT migliaccios isobesityinwomenprotectiveagainstosteoporosis
AT grecoea isobesityinwomenprotectiveagainstosteoporosis
AT fornarir isobesityinwomenprotectiveagainstosteoporosis
AT doninilm isobesityinwomenprotectiveagainstosteoporosis
AT lenzia isobesityinwomenprotectiveagainstosteoporosis
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