Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor

Little is known about the molecular mechanisms regulating neuron-specific alternative splicing. Here, the authors identify a combination of RNA-binding proteins regulating neuron-specific expression of the C. elegansinsulin receptor isoform DAF-2c and find disrupting these factors leads to learning...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Masahiro Tomioka, Yasuki Naito, Hidehito Kuroyanagi, Yuichi Iino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/f7e369aae40f41fea88f2ff8964a662b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Little is known about the molecular mechanisms regulating neuron-specific alternative splicing. Here, the authors identify a combination of RNA-binding proteins regulating neuron-specific expression of the C. elegansinsulin receptor isoform DAF-2c and find disrupting these factors leads to learning deficits.