Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor

Little is known about the molecular mechanisms regulating neuron-specific alternative splicing. Here, the authors identify a combination of RNA-binding proteins regulating neuron-specific expression of the C. elegansinsulin receptor isoform DAF-2c and find disrupting these factors leads to learning...

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Autores principales:	Masahiro Tomioka, Yasuki Naito, Hidehito Kuroyanagi, Yuichi Iino
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f7e369aae40f41fea88f2ff8964a662b
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spelling	oai:doaj.org-article:f7e369aae40f41fea88f2ff8964a662b2021-12-02T15:35:20ZSplicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor10.1038/ncomms116452041-1723https://doaj.org/article/f7e369aae40f41fea88f2ff8964a662b2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11645https://doaj.org/toc/2041-1723Little is known about the molecular mechanisms regulating neuron-specific alternative splicing. Here, the authors identify a combination of RNA-binding proteins regulating neuron-specific expression of the C. elegansinsulin receptor isoform DAF-2c and find disrupting these factors leads to learning deficits.Masahiro TomiokaYasuki NaitoHidehito KuroyanagiYuichi IinoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Masahiro Tomioka Yasuki Naito Hidehito Kuroyanagi Yuichi Iino Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor
description	Little is known about the molecular mechanisms regulating neuron-specific alternative splicing. Here, the authors identify a combination of RNA-binding proteins regulating neuron-specific expression of the C. elegansinsulin receptor isoform DAF-2c and find disrupting these factors leads to learning deficits.
format	article
author	Masahiro Tomioka Yasuki Naito Hidehito Kuroyanagi Yuichi Iino
author_facet	Masahiro Tomioka Yasuki Naito Hidehito Kuroyanagi Yuichi Iino
author_sort	Masahiro Tomioka
title	Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor
title_short	Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor
title_full	Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor
title_fullStr	Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor
title_full_unstemmed	Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor
title_sort	splicing factors control c. elegans behavioural learning in a single neuron by producing daf-2c receptor
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f7e369aae40f41fea88f2ff8964a662b
work_keys_str_mv	AT masahirotomioka splicingfactorscontrolcelegansbehaviourallearninginasingleneuronbyproducingdaf2creceptor AT yasukinaito splicingfactorscontrolcelegansbehaviourallearninginasingleneuronbyproducingdaf2creceptor AT hidehitokuroyanagi splicingfactorscontrolcelegansbehaviourallearninginasingleneuronbyproducingdaf2creceptor AT yuichiiino splicingfactorscontrolcelegansbehaviourallearninginasingleneuronbyproducingdaf2creceptor
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Splicing factors control C. elegans behavioural learning in a single neuron by producing DAF-2c receptor

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