Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life

Prior evidence suggested mesenchymal stromal cells (MSCs) required for skeletal formation, maintenance, and repair arise postnatally. Here, the authors show that Hoxa11 lineage-marked cells give rise to all skeletal lineages from embryogenesis through adulthood and are upstream progenitors of LepR-...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kyriel M. Pineault, Jane Y. Song, Kenneth M. Kozloff, Daniel Lucas, Deneen M. Wellik
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f7ea0e26660043b5baab7d27f61badf5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f7ea0e26660043b5baab7d27f61badf5
record_format	dspace
spelling	oai:doaj.org-article:f7ea0e26660043b5baab7d27f61badf52021-12-02T16:58:26ZHox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life10.1038/s41467-019-11100-42041-1723https://doaj.org/article/f7ea0e26660043b5baab7d27f61badf52019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11100-4https://doaj.org/toc/2041-1723Prior evidence suggested mesenchymal stromal cells (MSCs) required for skeletal formation, maintenance, and repair arise postnatally. Here, the authors show that Hoxa11 lineage-marked cells give rise to all skeletal lineages from embryogenesis through adulthood and are upstream progenitors of LepR- and Osx-lineage MSCsKyriel M. PineaultJane Y. SongKenneth M. KozloffDaniel LucasDeneen M. WellikNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyriel M. Pineault Jane Y. Song Kenneth M. Kozloff Daniel Lucas Deneen M. Wellik Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
description	Prior evidence suggested mesenchymal stromal cells (MSCs) required for skeletal formation, maintenance, and repair arise postnatally. Here, the authors show that Hoxa11 lineage-marked cells give rise to all skeletal lineages from embryogenesis through adulthood and are upstream progenitors of LepR- and Osx-lineage MSCs
format	article
author	Kyriel M. Pineault Jane Y. Song Kenneth M. Kozloff Daniel Lucas Deneen M. Wellik
author_facet	Kyriel M. Pineault Jane Y. Song Kenneth M. Kozloff Daniel Lucas Deneen M. Wellik
author_sort	Kyriel M. Pineault
title	Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
title_short	Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
title_full	Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
title_fullStr	Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
title_full_unstemmed	Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
title_sort	hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f7ea0e26660043b5baab7d27f61badf5
work_keys_str_mv	AT kyrielmpineault hox11expressingregionalskeletalstemcellsareprogenitorsforosteoblastschondrocytesandadipocytesthroughoutlife AT janeysong hox11expressingregionalskeletalstemcellsareprogenitorsforosteoblastschondrocytesandadipocytesthroughoutlife AT kennethmkozloff hox11expressingregionalskeletalstemcellsareprogenitorsforosteoblastschondrocytesandadipocytesthroughoutlife AT daniellucas hox11expressingregionalskeletalstemcellsareprogenitorsforosteoblastschondrocytesandadipocytesthroughoutlife AT deneenmwellik hox11expressingregionalskeletalstemcellsareprogenitorsforosteoblastschondrocytesandadipocytesthroughoutlife
_version_	1718382365802233856

Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life

Ejemplares similares