Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life
Prior evidence suggested mesenchymal stromal cells (MSCs) required for skeletal formation, maintenance, and repair arise postnatally. Here, the authors show that Hoxa11 lineage-marked cells give rise to all skeletal lineages from embryogenesis through adulthood and are upstream progenitors of LepR-...
Saved in:
Main Authors: | Kyriel M. Pineault, Jane Y. Song, Kenneth M. Kozloff, Daniel Lucas, Deneen M. Wellik |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/f7ea0e26660043b5baab7d27f61badf5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Lung Elastin Matrix Undergoes Rapid Degradation Upon Adult Loss of Hox5 Function
by: Mu-Hang Li, et al.
Published: (2021) -
Surface Modification of Carbon Nanofibers to Improve Their Biocompatibility in Contact with Osteoblast and Chondrocytes Cell Lines
by: Wojciech Smolka, et al.
Published: (2021) -
Ubiquitin specific peptidase Usp53 regulates osteoblast versus adipocyte lineage commitment
by: Hadla Hariri, et al.
Published: (2021) -
Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function
by: Daniel C. Berry, et al.
Published: (2016) -
Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
by: Gabriel B. Ferguson, et al.
Published: (2018)