Developmental potential of aneuploid human embryos cultured beyond implantation

Aneuploidy, abnormal chromosome number, is a major cause of early pregnancy loss. Here the authors determine the extent of post-implantation development of human embryos with common aneuploidies in culture, finding developmental arrest of monosomy 21 embryos, and trophoblast hypo-proliferation in tr...

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Bibliographic Details
Main Authors: Marta N. Shahbazi, Tianren Wang, Xin Tao, Bailey A. T. Weatherbee, Li Sun, Yiping Zhan, Laura Keller, Gary D. Smith, Antonio Pellicer, Richard T. Scott, Emre Seli, Magdalena Zernicka-Goetz
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/f7ed59a03a7948919b6f685226479c9b
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