Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia
Local anesthetic sustained release systems suffer from untriggered rapid drug release upon application. Here the authors overcome this issue by covalently linking tetracaine to a polymer gel via a photo-cleavable linkage, enabling light-triggered and repeatable drug release.
Guardado en:
Autores principales: | Wei Zhang, Tianjiao Ji, Yang Li, Yueqin Zheng, Manisha Mehta, Chao Zhao, Andong Liu, Daniel S. Kohane |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/f7f5610bdcbc4f8d89c158cdd6ef884d |
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