Survival of chronic hemodialysis patients over 80 years of age

Branka Sladoje-Martinovic, Ivana Mikolasevic, Ivan Bubic, Sanjin Racki, Lidija OrlicDepartment of Nephrology and Dialysis, Division of Internal Medicine, University Hospital Center Rijeka, Rijeka, CroatiaBackground/aim: The number of elderly patients with chronic kidney disease (CKD) stage 5 managem...

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Autores principales:	Sladoje-Martinovic B, Mikolasevic I, Bubic I, Racki S, Orlic L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	chronic kidney disease hemodialysis elderly patients Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/f7fcbbd80083432d9db1df0e2db37909
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spelling	oai:doaj.org-article:f7fcbbd80083432d9db1df0e2db379092021-12-02T09:32:38ZSurvival of chronic hemodialysis patients over 80 years of age1178-1998https://doaj.org/article/f7fcbbd80083432d9db1df0e2db379092014-04-01T00:00:00Zhttps://www.dovepress.com/survival-of-chronic-hemodialysis-patients-over-80-years-of-age-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Branka Sladoje-Martinovic, Ivana Mikolasevic, Ivan Bubic, Sanjin Racki, Lidija OrlicDepartment of Nephrology and Dialysis, Division of Internal Medicine, University Hospital Center Rijeka, Rijeka, CroatiaBackground/aim: The number of elderly patients with chronic kidney disease (CKD) stage 5 management with hemodialysis (HD) is steadily increasing. Therefore we analyzed the number of new CKD patients ≥80 years managed with HD and their survival through the study period. We aimed also, to identify which of several key variables might be independently associated with survival in this very elderly population of patients.Patients and methods: This was a single-center, retrospective cohort study that took place during the period from January 1987 to September 2012. The study consisted of 78 (50 male and 28 women) very elderly patients (≥80 years of age); the mean age at which HD was initiated was 83.2±2.5 years. Survival and factors associated with mortality were studied. Survival was defined as the time from start of HD treatment to death (or end of study, if still alive).Results: In the period from 1987 to 2002, patients ≥80 years of age were only sporadically treated with HD, but since 2003, the number of new patients has been steadily increasing. The mean survival for our group of patients was 25.1±22.4 months (range 1–115 months). Furthermore, 30.8% patients survived <12 months, 29.5% patients survived 12–24 months, 30.8% patients survived 24–60 months, and 9% patients survived >60 months on HD treatment. Older patients were less likely to have diabetes, and primary renal disease did not influence survival. Patients with high C-reactive protein levels and poor nutritional status, as well as those who did not have pre-HD nephrology care and those that had a catheter as vascular access for HD had poor survival. In about half of our patients, the cause of death was cardiovascular disease.Conclusion: Among patients who were ≥80 years of age at the start of HD treatment, those who received pre-HD nephrology care that followed a planned management pathway, those who had a good nutritional status, and those with an arteriovenous fistula as vascular access for HD at the time of HD initiation had a better survival.Keywords: chronic kidney disease, elderly patients, pre-HD nephrology care, nutritional status, arteriovenous fistulaSladoje-Martinovic BMikolasevic IBubic IRacki SOrlic LDove Medical Pressarticlechronic kidney diseasehemodialysiselderly patientsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 689-696 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	chronic kidney disease hemodialysis elderly patients Geriatrics RC952-954.6
spellingShingle	chronic kidney disease hemodialysis elderly patients Geriatrics RC952-954.6 Sladoje-Martinovic B Mikolasevic I Bubic I Racki S Orlic L Survival of chronic hemodialysis patients over 80 years of age
description	Branka Sladoje-Martinovic, Ivana Mikolasevic, Ivan Bubic, Sanjin Racki, Lidija OrlicDepartment of Nephrology and Dialysis, Division of Internal Medicine, University Hospital Center Rijeka, Rijeka, CroatiaBackground/aim: The number of elderly patients with chronic kidney disease (CKD) stage 5 management with hemodialysis (HD) is steadily increasing. Therefore we analyzed the number of new CKD patients ≥80 years managed with HD and their survival through the study period. We aimed also, to identify which of several key variables might be independently associated with survival in this very elderly population of patients.Patients and methods: This was a single-center, retrospective cohort study that took place during the period from January 1987 to September 2012. The study consisted of 78 (50 male and 28 women) very elderly patients (≥80 years of age); the mean age at which HD was initiated was 83.2±2.5 years. Survival and factors associated with mortality were studied. Survival was defined as the time from start of HD treatment to death (or end of study, if still alive).Results: In the period from 1987 to 2002, patients ≥80 years of age were only sporadically treated with HD, but since 2003, the number of new patients has been steadily increasing. The mean survival for our group of patients was 25.1±22.4 months (range 1–115 months). Furthermore, 30.8% patients survived <12 months, 29.5% patients survived 12–24 months, 30.8% patients survived 24–60 months, and 9% patients survived >60 months on HD treatment. Older patients were less likely to have diabetes, and primary renal disease did not influence survival. Patients with high C-reactive protein levels and poor nutritional status, as well as those who did not have pre-HD nephrology care and those that had a catheter as vascular access for HD had poor survival. In about half of our patients, the cause of death was cardiovascular disease.Conclusion: Among patients who were ≥80 years of age at the start of HD treatment, those who received pre-HD nephrology care that followed a planned management pathway, those who had a good nutritional status, and those with an arteriovenous fistula as vascular access for HD at the time of HD initiation had a better survival.Keywords: chronic kidney disease, elderly patients, pre-HD nephrology care, nutritional status, arteriovenous fistula
format	article
author	Sladoje-Martinovic B Mikolasevic I Bubic I Racki S Orlic L
author_facet	Sladoje-Martinovic B Mikolasevic I Bubic I Racki S Orlic L
author_sort	Sladoje-Martinovic B
title	Survival of chronic hemodialysis patients over 80 years of age
title_short	Survival of chronic hemodialysis patients over 80 years of age
title_full	Survival of chronic hemodialysis patients over 80 years of age
title_fullStr	Survival of chronic hemodialysis patients over 80 years of age
title_full_unstemmed	Survival of chronic hemodialysis patients over 80 years of age
title_sort	survival of chronic hemodialysis patients over 80 years of age
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/f7fcbbd80083432d9db1df0e2db37909
work_keys_str_mv	AT sladojemartinovicb survivalofchronichemodialysispatientsover80yearsofage AT mikolasevici survivalofchronichemodialysispatientsover80yearsofage AT bubici survivalofchronichemodialysispatientsover80yearsofage AT rackis survivalofchronichemodialysispatientsover80yearsofage AT orlicl survivalofchronichemodialysispatientsover80yearsofage
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Survival of chronic hemodialysis patients over 80 years of age

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