Preparation, structure and activity of polysaccharide phosphate esters

Polysaccharides have anti-virus, anti-cancer, anti-oxidation, immune regulation, hypoglycemia and other biological activities. Because of their safety, fewer side effects and other advantages, polysaccharides are considered as ideal raw materials in food and drugs. The biological activity of polysac...

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Autores principales:	Shiyang Zhou, Gangliang Huang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Phosphorylated polysaccharide Structural characteristics Biological activity Structure-activity relationship Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/f80aca91b84d4c029de1d199ff3c99bb
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spelling	oai:doaj.org-article:f80aca91b84d4c029de1d199ff3c99bb2021-11-14T04:29:52ZPreparation, structure and activity of polysaccharide phosphate esters0753-332210.1016/j.biopha.2021.112332https://doaj.org/article/f80aca91b84d4c029de1d199ff3c99bb2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0753332221011161https://doaj.org/toc/0753-3322Polysaccharides have anti-virus, anti-cancer, anti-oxidation, immune regulation, hypoglycemia and other biological activities. Because of their safety, fewer side effects and other advantages, polysaccharides are considered as ideal raw materials in food and drugs. The biological activity of polysaccharides can be improved by structural modification (such as sulfation, carboxymethylation, phosphorylation, etc.), and even new biological activity can be generated. In this review, the recent advances in the phosphorylation of polysaccharides were reviewed from the perspectives of modification methods, structures, biological activities and structure-activity relationships.Shiyang ZhouGangliang HuangElsevierarticlePhosphorylated polysaccharideStructural characteristicsBiological activityStructure-activity relationshipTherapeutics. PharmacologyRM1-950ENBiomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112332- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Phosphorylated polysaccharide Structural characteristics Biological activity Structure-activity relationship Therapeutics. Pharmacology RM1-950
spellingShingle	Phosphorylated polysaccharide Structural characteristics Biological activity Structure-activity relationship Therapeutics. Pharmacology RM1-950 Shiyang Zhou Gangliang Huang Preparation, structure and activity of polysaccharide phosphate esters
description	Polysaccharides have anti-virus, anti-cancer, anti-oxidation, immune regulation, hypoglycemia and other biological activities. Because of their safety, fewer side effects and other advantages, polysaccharides are considered as ideal raw materials in food and drugs. The biological activity of polysaccharides can be improved by structural modification (such as sulfation, carboxymethylation, phosphorylation, etc.), and even new biological activity can be generated. In this review, the recent advances in the phosphorylation of polysaccharides were reviewed from the perspectives of modification methods, structures, biological activities and structure-activity relationships.
format	article
author	Shiyang Zhou Gangliang Huang
author_facet	Shiyang Zhou Gangliang Huang
author_sort	Shiyang Zhou
title	Preparation, structure and activity of polysaccharide phosphate esters
title_short	Preparation, structure and activity of polysaccharide phosphate esters
title_full	Preparation, structure and activity of polysaccharide phosphate esters
title_fullStr	Preparation, structure and activity of polysaccharide phosphate esters
title_full_unstemmed	Preparation, structure and activity of polysaccharide phosphate esters
title_sort	preparation, structure and activity of polysaccharide phosphate esters
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/f80aca91b84d4c029de1d199ff3c99bb
work_keys_str_mv	AT shiyangzhou preparationstructureandactivityofpolysaccharidephosphateesters AT ganglianghuang preparationstructureandactivityofpolysaccharidephosphateesters
_version_	1718430053623136256

Preparation, structure and activity of polysaccharide phosphate esters

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