Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization

Borrelia burgdorferi, the causative agent of Lyme disease, is transmitted by the tick Ixodes scapularis. Here, the authors show that a tick secreted protein (PIXR) modulates the tick gut microbiota and facilitates B. burgdorferi colonization.

Guardado en:
Detalles Bibliográficos
Autores principales: Sukanya Narasimhan, Tim J. Schuijt, Nabil M. Abraham, Nallakkandi Rajeevan, Jeroen Coumou, Morven Graham, Andrew Robson, Ming-Jie Wu, Sirlei Daffre, Joppe W. Hovius, Erol Fikrig
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/f8125e0a31f24597bc975085a2deecbb
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:f8125e0a31f24597bc975085a2deecbb
record_format dspace
spelling oai:doaj.org-article:f8125e0a31f24597bc975085a2deecbb2021-12-02T13:57:55ZModulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization10.1038/s41467-017-00208-02041-1723https://doaj.org/article/f8125e0a31f24597bc975085a2deecbb2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00208-0https://doaj.org/toc/2041-1723Borrelia burgdorferi, the causative agent of Lyme disease, is transmitted by the tick Ixodes scapularis. Here, the authors show that a tick secreted protein (PIXR) modulates the tick gut microbiota and facilitates B. burgdorferi colonization.Sukanya NarasimhanTim J. SchuijtNabil M. AbrahamNallakkandi RajeevanJeroen CoumouMorven GrahamAndrew RobsonMing-Jie WuSirlei DaffreJoppe W. HoviusErol FikrigNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sukanya Narasimhan
Tim J. Schuijt
Nabil M. Abraham
Nallakkandi Rajeevan
Jeroen Coumou
Morven Graham
Andrew Robson
Ming-Jie Wu
Sirlei Daffre
Joppe W. Hovius
Erol Fikrig
Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization
description Borrelia burgdorferi, the causative agent of Lyme disease, is transmitted by the tick Ixodes scapularis. Here, the authors show that a tick secreted protein (PIXR) modulates the tick gut microbiota and facilitates B. burgdorferi colonization.
format article
author Sukanya Narasimhan
Tim J. Schuijt
Nabil M. Abraham
Nallakkandi Rajeevan
Jeroen Coumou
Morven Graham
Andrew Robson
Ming-Jie Wu
Sirlei Daffre
Joppe W. Hovius
Erol Fikrig
author_facet Sukanya Narasimhan
Tim J. Schuijt
Nabil M. Abraham
Nallakkandi Rajeevan
Jeroen Coumou
Morven Graham
Andrew Robson
Ming-Jie Wu
Sirlei Daffre
Joppe W. Hovius
Erol Fikrig
author_sort Sukanya Narasimhan
title Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization
title_short Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization
title_full Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization
title_fullStr Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization
title_full_unstemmed Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization
title_sort modulation of the tick gut milieu by a secreted tick protein favors borrelia burgdorferi colonization
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/f8125e0a31f24597bc975085a2deecbb
work_keys_str_mv AT sukanyanarasimhan modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT timjschuijt modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT nabilmabraham modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT nallakkandirajeevan modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT jeroencoumou modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT morvengraham modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT andrewrobson modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT mingjiewu modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT sirleidaffre modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT joppewhovius modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
AT erolfikrig modulationofthetickgutmilieubyasecretedtickproteinfavorsborreliaburgdorfericolonization
_version_ 1718392296209121280