Fluctuation analysis: can estimates be trusted?
The estimation of mutation rates and relative fitnesses in fluctuation analysis is based on the unrealistic hypothesis that the single-cell times to division are exponentially distributed. Using the classical Luria-Delbrück distribution outside its modelling hypotheses induces an important bias on t...
Saved in:
| Main Author: | |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2013
|
| Subjects: | |
| Online Access: | https://doaj.org/article/f815483004e943b5be958c02484acabe |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|