The BRD9/7 Inhibitor TP-472 Blocks Melanoma Tumor Growth by Suppressing ECM-Mediated Oncogenic Signaling and Inducing Apoptosis
Melanoma accounts for the majority of all skin cancer-related deaths and only 1/3rd of melanoma patients with distal metastasis survive beyond five years. However, current therapies including BRAF/MEK targeted therapies or immunotherapies only benefit a subset of melanoma patients due to the emergen...
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Auteurs principaux: | Lawrence David Mason, Suresh Chava, Kiran Kumar Reddi, Romi Gupta |
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Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/f816bc3dd434425bb9f56253d5058512 |
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