Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling

Retrotransposons are known to be involved in aging. Here the authors show that the retrotransposon silencer Piwi contributes to germline stem cell loss during aging in Drosophila.

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Autores principales:	Kun-Yang Lin, Wen-Der Wang, Chi-Hung Lin, Elham Rastegari, Yu-Han Su, Yu-Tzu Chang, Yung-Feng Liao, Yi-Chieh Chang, Haiwei Pi, Bo-Yi Yu, Shu-Hwa Chen, Chung-Yen Lin, Mei-Yeh Lu, Tsu-Yi Su, Fei-Yang Tzou, Chih-Chiang Chan, Hwei-Jan Hsu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f818031002264c058f9fd632e6d09a5a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:f818031002264c058f9fd632e6d09a5a2021-12-02T16:04:12ZPiwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling10.1038/s41467-020-16858-62041-1723https://doaj.org/article/f818031002264c058f9fd632e6d09a5a2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16858-6https://doaj.org/toc/2041-1723Retrotransposons are known to be involved in aging. Here the authors show that the retrotransposon silencer Piwi contributes to germline stem cell loss during aging in Drosophila.Kun-Yang LinWen-Der WangChi-Hung LinElham RastegariYu-Han SuYu-Tzu ChangYung-Feng LiaoYi-Chieh ChangHaiwei PiBo-Yi YuShu-Hwa ChenChung-Yen LinMei-Yeh LuTsu-Yi SuFei-Yang TzouChih-Chiang ChanHwei-Jan HsuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kun-Yang Lin Wen-Der Wang Chi-Hung Lin Elham Rastegari Yu-Han Su Yu-Tzu Chang Yung-Feng Liao Yi-Chieh Chang Haiwei Pi Bo-Yi Yu Shu-Hwa Chen Chung-Yen Lin Mei-Yeh Lu Tsu-Yi Su Fei-Yang Tzou Chih-Chiang Chan Hwei-Jan Hsu Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
description	Retrotransposons are known to be involved in aging. Here the authors show that the retrotransposon silencer Piwi contributes to germline stem cell loss during aging in Drosophila.
format	article
author	Kun-Yang Lin Wen-Der Wang Chi-Hung Lin Elham Rastegari Yu-Han Su Yu-Tzu Chang Yung-Feng Liao Yi-Chieh Chang Haiwei Pi Bo-Yi Yu Shu-Hwa Chen Chung-Yen Lin Mei-Yeh Lu Tsu-Yi Su Fei-Yang Tzou Chih-Chiang Chan Hwei-Jan Hsu
author_facet	Kun-Yang Lin Wen-Der Wang Chi-Hung Lin Elham Rastegari Yu-Han Su Yu-Tzu Chang Yung-Feng Liao Yi-Chieh Chang Haiwei Pi Bo-Yi Yu Shu-Hwa Chen Chung-Yen Lin Mei-Yeh Lu Tsu-Yi Su Fei-Yang Tzou Chih-Chiang Chan Hwei-Jan Hsu
author_sort	Kun-Yang Lin
title	Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
title_short	Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
title_full	Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
title_fullStr	Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
title_full_unstemmed	Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
title_sort	piwi reduction in the aged niche eliminates germline stem cells via toll-gsk3 signaling
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f818031002264c058f9fd632e6d09a5a
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Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling

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