Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling

Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling

Retrotransposons are known to be involved in aging. Here the authors show that the retrotransposon silencer Piwi contributes to germline stem cell loss during aging in Drosophila.

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Détails bibliographiques
Auteurs principaux: Kun-Yang Lin, Wen-Der Wang, Chi-Hung Lin, Elham Rastegari, Yu-Han Su, Yu-Tzu Chang, Yung-Feng Liao, Yi-Chieh Chang, Haiwei Pi, Bo-Yi Yu, Shu-Hwa Chen, Chung-Yen Lin, Mei-Yeh Lu, Tsu-Yi Su, Fei-Yang Tzou, Chih-Chiang Chan, Hwei-Jan Hsu
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/f818031002264c058f9fd632e6d09a5a
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