The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction

Pupariation in Drosophila is triggered by the steroid-hormone ecdysone and requires coordination between associated behavioral and body-reshaping motor subprograms. The authors show that coordination requires ecdysone-dependent Dilp8-Lgr3 signaling between the cuticle epidermis and interneurons.

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Autores principales: Fabiana Heredia, Yanel Volonté, Joana Pereirinha, Magdalena Fernandez-Acosta, Andreia P. Casimiro, Cláudia G. Belém, Filipe Viegas, Kohtaro Tanaka, Juliane Menezes, Maite Arana, Gisele A. Cardoso, André Macedo, Malwina Kotowicz, Facundo H. Prado Spalm, Marcos J. Dibo, Raquel D. Monfardini, Tatiana T. Torres, César S. Mendes, Andres Garelli, Alisson M. Gontijo
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f822d3a3ff054af8a43f277e88d9af21
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spelling oai:doaj.org-article:f822d3a3ff054af8a43f277e88d9af212021-12-02T17:52:09ZThe steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction10.1038/s41467-021-23218-52041-1723https://doaj.org/article/f822d3a3ff054af8a43f277e88d9af212021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23218-5https://doaj.org/toc/2041-1723Pupariation in Drosophila is triggered by the steroid-hormone ecdysone and requires coordination between associated behavioral and body-reshaping motor subprograms. The authors show that coordination requires ecdysone-dependent Dilp8-Lgr3 signaling between the cuticle epidermis and interneurons.Fabiana HerediaYanel VolontéJoana PereirinhaMagdalena Fernandez-AcostaAndreia P. CasimiroCláudia G. BelémFilipe ViegasKohtaro TanakaJuliane MenezesMaite AranaGisele A. CardosoAndré MacedoMalwina KotowiczFacundo H. Prado SpalmMarcos J. DiboRaquel D. MonfardiniTatiana T. TorresCésar S. MendesAndres GarelliAlisson M. GontijoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fabiana Heredia
Yanel Volonté
Joana Pereirinha
Magdalena Fernandez-Acosta
Andreia P. Casimiro
Cláudia G. Belém
Filipe Viegas
Kohtaro Tanaka
Juliane Menezes
Maite Arana
Gisele A. Cardoso
André Macedo
Malwina Kotowicz
Facundo H. Prado Spalm
Marcos J. Dibo
Raquel D. Monfardini
Tatiana T. Torres
César S. Mendes
Andres Garelli
Alisson M. Gontijo
The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction
description Pupariation in Drosophila is triggered by the steroid-hormone ecdysone and requires coordination between associated behavioral and body-reshaping motor subprograms. The authors show that coordination requires ecdysone-dependent Dilp8-Lgr3 signaling between the cuticle epidermis and interneurons.
format article
author Fabiana Heredia
Yanel Volonté
Joana Pereirinha
Magdalena Fernandez-Acosta
Andreia P. Casimiro
Cláudia G. Belém
Filipe Viegas
Kohtaro Tanaka
Juliane Menezes
Maite Arana
Gisele A. Cardoso
André Macedo
Malwina Kotowicz
Facundo H. Prado Spalm
Marcos J. Dibo
Raquel D. Monfardini
Tatiana T. Torres
César S. Mendes
Andres Garelli
Alisson M. Gontijo
author_facet Fabiana Heredia
Yanel Volonté
Joana Pereirinha
Magdalena Fernandez-Acosta
Andreia P. Casimiro
Cláudia G. Belém
Filipe Viegas
Kohtaro Tanaka
Juliane Menezes
Maite Arana
Gisele A. Cardoso
André Macedo
Malwina Kotowicz
Facundo H. Prado Spalm
Marcos J. Dibo
Raquel D. Monfardini
Tatiana T. Torres
César S. Mendes
Andres Garelli
Alisson M. Gontijo
author_sort Fabiana Heredia
title The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction
title_short The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction
title_full The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction
title_fullStr The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction
title_full_unstemmed The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction
title_sort steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron dilp8-lgr3 signal induction
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f822d3a3ff054af8a43f277e88d9af21
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