Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain

The WD40 domain of ATG16L1 is thought to be involved in non-canonical autophagy. Here the authors screen peptide libraries and identify interactions between this domain and the IL-2Rγ and IL-10RB receptors, indicating endosomal regulation of cytokine signalling by non-canonical autophagy.

Guardado en:

Detalles Bibliográficos
Autores principales:	Inmaculada Serramito-Gómez, Emilio Boada-Romero, Raquel Villamuera, Álvaro Fernández-Cabrera, José Luis Cedillo, Ángela Martín-Regalado, Simon Carding, Uli Mayer, Penny P. Powell, Thomas Wileman, Irene García-Higuera, Felipe X. Pimentel-Muiños
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f827951d5bc9452e960cbed014b2d5d6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f827951d5bc9452e960cbed014b2d5d6
record_format	dspace
spelling	oai:doaj.org-article:f827951d5bc9452e960cbed014b2d5d62021-12-02T17:31:41ZRegulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain10.1038/s41467-020-19670-42041-1723https://doaj.org/article/f827951d5bc9452e960cbed014b2d5d62020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19670-4https://doaj.org/toc/2041-1723The WD40 domain of ATG16L1 is thought to be involved in non-canonical autophagy. Here the authors screen peptide libraries and identify interactions between this domain and the IL-2Rγ and IL-10RB receptors, indicating endosomal regulation of cytokine signalling by non-canonical autophagy.Inmaculada Serramito-GómezEmilio Boada-RomeroRaquel VillamueraÁlvaro Fernández-CabreraJosé Luis CedilloÁngela Martín-RegaladoSimon CardingUli MayerPenny P. PowellThomas WilemanIrene García-HigueraFelipe X. Pimentel-MuiñosNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Inmaculada Serramito-Gómez Emilio Boada-Romero Raquel Villamuera Álvaro Fernández-Cabrera José Luis Cedillo Ángela Martín-Regalado Simon Carding Uli Mayer Penny P. Powell Thomas Wileman Irene García-Higuera Felipe X. Pimentel-Muiños Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
description	The WD40 domain of ATG16L1 is thought to be involved in non-canonical autophagy. Here the authors screen peptide libraries and identify interactions between this domain and the IL-2Rγ and IL-10RB receptors, indicating endosomal regulation of cytokine signalling by non-canonical autophagy.
format	article
author	Inmaculada Serramito-Gómez Emilio Boada-Romero Raquel Villamuera Álvaro Fernández-Cabrera José Luis Cedillo Ángela Martín-Regalado Simon Carding Uli Mayer Penny P. Powell Thomas Wileman Irene García-Higuera Felipe X. Pimentel-Muiños
author_facet	Inmaculada Serramito-Gómez Emilio Boada-Romero Raquel Villamuera Álvaro Fernández-Cabrera José Luis Cedillo Ángela Martín-Regalado Simon Carding Uli Mayer Penny P. Powell Thomas Wileman Irene García-Higuera Felipe X. Pimentel-Muiños
author_sort	Inmaculada Serramito-Gómez
title	Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
title_short	Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
title_full	Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
title_fullStr	Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
title_full_unstemmed	Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
title_sort	regulation of cytokine signaling through direct interaction between cytokine receptors and the atg16l1 wd40 domain
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f827951d5bc9452e960cbed014b2d5d6
work_keys_str_mv	AT inmaculadaserramitogomez regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT emilioboadaromero regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT raquelvillamuera regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT alvarofernandezcabrera regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT joseluiscedillo regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT angelamartinregalado regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT simoncarding regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT ulimayer regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT pennyppowell regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT thomaswileman regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT irenegarciahiguera regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain AT felipexpimentelmuinos regulationofcytokinesignalingthroughdirectinteractionbetweencytokinereceptorsandtheatg16l1wd40domain
_version_	1718380590694137856

Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain

Ejemplares similares