Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
The WD40 domain of ATG16L1 is thought to be involved in non-canonical autophagy. Here the authors screen peptide libraries and identify interactions between this domain and the IL-2Rγ and IL-10RB receptors, indicating endosomal regulation of cytokine signalling by non-canonical autophagy.
Guardado en:
Autores principales: | Inmaculada Serramito-Gómez, Emilio Boada-Romero, Raquel Villamuera, Álvaro Fernández-Cabrera, José Luis Cedillo, Ángela Martín-Regalado, Simon Carding, Uli Mayer, Penny P. Powell, Thomas Wileman, Irene García-Higuera, Felipe X. Pimentel-Muiños |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f827951d5bc9452e960cbed014b2d5d6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1
por: Emilio Boada-Romero, et al.
Publicado: (2016) -
Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis
por: Karolina Slowicka, et al.
Publicado: (2019) -
W.D. Muhammad
por: Zafar Ishaq Ansari
Publicado: (1985) -
Identifying the hotspots on the top faces of WD40-repeat proteins from their primary sequences by β-bulges and DHSW tetrads.
por: Xian-Hui Wu, et al.
Publicado: (2012) - Cytokine