Viscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling

Abstract Biomodels made of poly(vinyl alcohol) (PVA) are demanded because they can represent the geometries and mechanical properties of human tissues realistically. Injecting and molding, commonly used in three-dimensional (3D) modeling, help to represent the blood vessels accurately. However, thes...

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Autores principales: Yasutomo Shimizu, Tadao Tanabe, Hiroshi Yoshida, Motohiro Kasuya, Tadao Matsunaga, Yoichi Haga, Kazue Kurihara, Makoto Ohta
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Publicado: Nature Portfolio 2018
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spelling oai:doaj.org-article:f829bc1ecf5d47b9ab6e6eeb4bafbed72021-12-02T15:08:24ZViscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling10.1038/s41598-018-34986-42045-2322https://doaj.org/article/f829bc1ecf5d47b9ab6e6eeb4bafbed72018-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-34986-4https://doaj.org/toc/2045-2322Abstract Biomodels made of poly(vinyl alcohol) (PVA) are demanded because they can represent the geometries and mechanical properties of human tissues realistically. Injecting and molding, commonly used in three-dimensional (3D) modeling, help to represent the blood vessels accurately. However, these techniques sometimes require higher pressures than the upper pressure limit of the dispensers for pouring in high viscosity materials; the material viscosity should therefore be lower. Moreover, the mechanical properties of the biomodels should be reproduced. This study proposes a PVA solution through the addition of xanthan gum (XG) for 3D modeling, which lowers liquid viscosity while maintaining the mechanical properties of biomodels. XG is known to facilitate the achievement of non-Newtonian fluidity; however, the effects of XG on a PVA solution and PVA hydrogel (PVA-H) are not confirmed. The viscosity measurement using 15 wt% PVA with XG solution (PVA/XG) shows that it will provide easier pouring than 17 wt% PVA solution. The tensile test using the PVA-H of PVA(15 wt%)/XG(0.2 wt%) reveals that the gel is comparable in Young’s modulus to 17 wt% PVA-H. X-ray diffraction shows the crystalline structures of the PVA/XG gel and PVA-H are identical. Thus, this PVA/XG would be useful for fabricating biomodels using injection molding techniques.Yasutomo ShimizuTadao TanabeHiroshi YoshidaMotohiro KasuyaTadao MatsunagaYoichi HagaKazue KuriharaMakoto OhtaNature PortfolioarticleVinyl AlcoholBiomodelsHigh Viscosity MaterialsShear Viscosity MeasurementsNippon Synthetic Chemical IndustryMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)
institution DOAJ
collection DOAJ
language EN
topic Vinyl Alcohol
Biomodels
High Viscosity Materials
Shear Viscosity Measurements
Nippon Synthetic Chemical Industry
Medicine
R
Science
Q
spellingShingle Vinyl Alcohol
Biomodels
High Viscosity Materials
Shear Viscosity Measurements
Nippon Synthetic Chemical Industry
Medicine
R
Science
Q
Yasutomo Shimizu
Tadao Tanabe
Hiroshi Yoshida
Motohiro Kasuya
Tadao Matsunaga
Yoichi Haga
Kazue Kurihara
Makoto Ohta
Viscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling
description Abstract Biomodels made of poly(vinyl alcohol) (PVA) are demanded because they can represent the geometries and mechanical properties of human tissues realistically. Injecting and molding, commonly used in three-dimensional (3D) modeling, help to represent the blood vessels accurately. However, these techniques sometimes require higher pressures than the upper pressure limit of the dispensers for pouring in high viscosity materials; the material viscosity should therefore be lower. Moreover, the mechanical properties of the biomodels should be reproduced. This study proposes a PVA solution through the addition of xanthan gum (XG) for 3D modeling, which lowers liquid viscosity while maintaining the mechanical properties of biomodels. XG is known to facilitate the achievement of non-Newtonian fluidity; however, the effects of XG on a PVA solution and PVA hydrogel (PVA-H) are not confirmed. The viscosity measurement using 15 wt% PVA with XG solution (PVA/XG) shows that it will provide easier pouring than 17 wt% PVA solution. The tensile test using the PVA-H of PVA(15 wt%)/XG(0.2 wt%) reveals that the gel is comparable in Young’s modulus to 17 wt% PVA-H. X-ray diffraction shows the crystalline structures of the PVA/XG gel and PVA-H are identical. Thus, this PVA/XG would be useful for fabricating biomodels using injection molding techniques.
format article
author Yasutomo Shimizu
Tadao Tanabe
Hiroshi Yoshida
Motohiro Kasuya
Tadao Matsunaga
Yoichi Haga
Kazue Kurihara
Makoto Ohta
author_facet Yasutomo Shimizu
Tadao Tanabe
Hiroshi Yoshida
Motohiro Kasuya
Tadao Matsunaga
Yoichi Haga
Kazue Kurihara
Makoto Ohta
author_sort Yasutomo Shimizu
title Viscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling
title_short Viscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling
title_full Viscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling
title_fullStr Viscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling
title_full_unstemmed Viscosity measurement of Xanthan–Poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3D modeling
title_sort viscosity measurement of xanthan–poly(vinyl alcohol) mixture and its effect on the mechanical properties of the hydrogel for 3d modeling
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f829bc1ecf5d47b9ab6e6eeb4bafbed7
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AT tadaotanabe viscositymeasurementofxanthanpolyvinylalcoholmixtureanditseffectonthemechanicalpropertiesofthehydrogelfor3dmodeling
AT hiroshiyoshida viscositymeasurementofxanthanpolyvinylalcoholmixtureanditseffectonthemechanicalpropertiesofthehydrogelfor3dmodeling
AT motohirokasuya viscositymeasurementofxanthanpolyvinylalcoholmixtureanditseffectonthemechanicalpropertiesofthehydrogelfor3dmodeling
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AT yoichihaga viscositymeasurementofxanthanpolyvinylalcoholmixtureanditseffectonthemechanicalpropertiesofthehydrogelfor3dmodeling
AT kazuekurihara viscositymeasurementofxanthanpolyvinylalcoholmixtureanditseffectonthemechanicalpropertiesofthehydrogelfor3dmodeling
AT makotoohta viscositymeasurementofxanthanpolyvinylalcoholmixtureanditseffectonthemechanicalpropertiesofthehydrogelfor3dmodeling
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