Structure of transcribing RNA polymerase II-nucleosome complex

Structure of transcribing RNA polymerase II-nucleosome complex

Eukaryotic transcription requires passage of RNA polymerase II (Pol II) through chromatin, which is impaired by nucleosomes. Here the authors report the cryo-EM structure of transcribing Pol II engaged with a downstream nucleosome core particle at an overall resolution of 4.4 Å, providing insights i...

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Autores principales: Lucas Farnung, Seychelle M. Vos, Patrick Cramer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/f832447ece5a402da1f4a0d40d65ef34
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