Structure of transcribing RNA polymerase II-nucleosome complex
Eukaryotic transcription requires passage of RNA polymerase II (Pol II) through chromatin, which is impaired by nucleosomes. Here the authors report the cryo-EM structure of transcribing Pol II engaged with a downstream nucleosome core particle at an overall resolution of 4.4 Å, providing insights i...
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Main Authors: | Lucas Farnung, Seychelle M. Vos, Patrick Cramer |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/f832447ece5a402da1f4a0d40d65ef34 |
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