Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy

The generation of biomimetic nanoparticles that retain the integrity of proteins has been a challenge. Here, the authors generate biomimetic nanoparticles that are exocytosed from tumour cells and show their therapeutic potential in targeting tumours and cancer stem cells in multiple mouse models.

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Autores principales:	Tuying Yong, Xiaoqiong Zhang, Nana Bie, Hongbo Zhang, Xuting Zhang, Fuying Li, Abdul Hakeem, Jun Hu, Lu Gan, Hélder A. Santos, Xiangliang Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f8349c0749544cf8bfcd1e3ea095962f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:f8349c0749544cf8bfcd1e3ea095962f2021-12-02T17:32:56ZTumor exosome-based nanoparticles are efficient drug carriers for chemotherapy10.1038/s41467-019-11718-42041-1723https://doaj.org/article/f8349c0749544cf8bfcd1e3ea095962f2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11718-4https://doaj.org/toc/2041-1723The generation of biomimetic nanoparticles that retain the integrity of proteins has been a challenge. Here, the authors generate biomimetic nanoparticles that are exocytosed from tumour cells and show their therapeutic potential in targeting tumours and cancer stem cells in multiple mouse models.Tuying YongXiaoqiong ZhangNana BieHongbo ZhangXuting ZhangFuying LiAbdul HakeemJun HuLu GanHélder A. SantosXiangliang YangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tuying Yong Xiaoqiong Zhang Nana Bie Hongbo Zhang Xuting Zhang Fuying Li Abdul Hakeem Jun Hu Lu Gan Hélder A. Santos Xiangliang Yang Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
description	The generation of biomimetic nanoparticles that retain the integrity of proteins has been a challenge. Here, the authors generate biomimetic nanoparticles that are exocytosed from tumour cells and show their therapeutic potential in targeting tumours and cancer stem cells in multiple mouse models.
format	article
author	Tuying Yong Xiaoqiong Zhang Nana Bie Hongbo Zhang Xuting Zhang Fuying Li Abdul Hakeem Jun Hu Lu Gan Hélder A. Santos Xiangliang Yang
author_facet	Tuying Yong Xiaoqiong Zhang Nana Bie Hongbo Zhang Xuting Zhang Fuying Li Abdul Hakeem Jun Hu Lu Gan Hélder A. Santos Xiangliang Yang
author_sort	Tuying Yong
title	Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
title_short	Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
title_full	Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
title_fullStr	Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
title_full_unstemmed	Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
title_sort	tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f8349c0749544cf8bfcd1e3ea095962f
work_keys_str_mv	AT tuyingyong tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT xiaoqiongzhang tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT nanabie tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT hongbozhang tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT xutingzhang tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT fuyingli tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT abdulhakeem tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT junhu tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT lugan tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT helderasantos tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy AT xiangliangyang tumorexosomebasednanoparticlesareefficientdrugcarriersforchemotherapy
_version_	1718380160359596032

Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy

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