Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer

Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer

Abstract The Newcastle disease virus (NDV) strain AF2240 is an avian avulavirus that has been demonstrated to possess oncolytic activity against cancer cells. However, to illicit a greater anti-cancer immune response, it is believed that the incorporation of immunostimulatory genes such as IL12 into...

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Autores principales: Zahiah Mohamed Amin, Muhamad Alhapis Che Ani, Sheau Wei Tan, Swee Keong Yeap, Noorjahan Banu Alitheen, Syed Umar Faruq Syed Najmuddin, Jeevanathan Kalyanasundram, Soon Choy Chan, Abhi Veerakumarasivam, Suet Lin Chia, Khatijah Yusoff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/f8373010fc52448aa4c9cec3b38903fd
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