The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1

Telomeres, tandem repeats at the ends of linear chromosomes, have evolved to deal with the end replication and end protection. Using a proteomics approach, the authors identify TEBP-1 and TEBP-2, two double-stranded binding proteins which together are required for fertility. Despite being paralogs,...

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Autores principales:	Sabrina Dietz, Miguel Vasconcelos Almeida, Emily Nischwitz, Jan Schreier, Nikenza Viceconte, Albert Fradera-Sola, Christian Renz, Alejandro Ceron-Noriega, Helle D. Ulrich, Dennis Kappei, René F. Ketting, Falk Butter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f83ddf084bc149738d2f2680d08fdb42
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spelling	oai:doaj.org-article:f83ddf084bc149738d2f2680d08fdb422021-12-02T15:36:28ZThe double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-110.1038/s41467-021-22861-22041-1723https://doaj.org/article/f83ddf084bc149738d2f2680d08fdb422021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22861-2https://doaj.org/toc/2041-1723Telomeres, tandem repeats at the ends of linear chromosomes, have evolved to deal with the end replication and end protection. Using a proteomics approach, the authors identify TEBP-1 and TEBP-2, two double-stranded binding proteins which together are required for fertility. Despite being paralogs, they have distinct individual effects on telomere dynamics; TEBP-1 and TEBP-2 are part of a telomeric complex also containing POT-1.Sabrina DietzMiguel Vasconcelos AlmeidaEmily NischwitzJan SchreierNikenza ViceconteAlbert Fradera-SolaChristian RenzAlejandro Ceron-NoriegaHelle D. UlrichDennis KappeiRené F. KettingFalk ButterNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sabrina Dietz Miguel Vasconcelos Almeida Emily Nischwitz Jan Schreier Nikenza Viceconte Albert Fradera-Sola Christian Renz Alejandro Ceron-Noriega Helle D. Ulrich Dennis Kappei René F. Ketting Falk Butter The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
description	Telomeres, tandem repeats at the ends of linear chromosomes, have evolved to deal with the end replication and end protection. Using a proteomics approach, the authors identify TEBP-1 and TEBP-2, two double-stranded binding proteins which together are required for fertility. Despite being paralogs, they have distinct individual effects on telomere dynamics; TEBP-1 and TEBP-2 are part of a telomeric complex also containing POT-1.
format	article
author	Sabrina Dietz Miguel Vasconcelos Almeida Emily Nischwitz Jan Schreier Nikenza Viceconte Albert Fradera-Sola Christian Renz Alejandro Ceron-Noriega Helle D. Ulrich Dennis Kappei René F. Ketting Falk Butter
author_facet	Sabrina Dietz Miguel Vasconcelos Almeida Emily Nischwitz Jan Schreier Nikenza Viceconte Albert Fradera-Sola Christian Renz Alejandro Ceron-Noriega Helle D. Ulrich Dennis Kappei René F. Ketting Falk Butter
author_sort	Sabrina Dietz
title	The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
title_short	The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
title_full	The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
title_fullStr	The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
title_full_unstemmed	The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
title_sort	double-stranded dna-binding proteins tebp-1 and tebp-2 form a telomeric complex with pot-1
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f83ddf084bc149738d2f2680d08fdb42
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The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1

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