Gammaherpesvirus infections in equids: a review

Maria Luisa Marenzoni,1 Valentina Stefanetti,1 Maria Luisa Danzetta,1 Peter Joseph Timoney21Department of Veterinary Medicine, University of Perugia, Perugia, Italy; 2Department of Veterinary Science, Maxwell H Gluck Equine Research Center, Lexington, KY, USAAbstract: Although the first equine gamm...

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Autores principales:	Marenzoni ML, Stefanetti V, Danzetta ML, Timoney PJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/f848ddfe2823464a9d25acd3d3f079aa
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spelling	oai:doaj.org-article:f848ddfe2823464a9d25acd3d3f079aa2021-12-02T01:16:13ZGammaherpesvirus infections in equids: a review2230-2034https://doaj.org/article/f848ddfe2823464a9d25acd3d3f079aa2015-04-01T00:00:00Zhttp://www.dovepress.com/gammaherpesvirus-infections-in-equids-a-review-peer-reviewed-article-VMRRhttps://doaj.org/toc/2230-2034 Maria Luisa Marenzoni,1 Valentina Stefanetti,1 Maria Luisa Danzetta,1 Peter Joseph Timoney21Department of Veterinary Medicine, University of Perugia, Perugia, Italy; 2Department of Veterinary Science, Maxwell H Gluck Equine Research Center, Lexington, KY, USAAbstract: Although the first equine gammaherpesvirus was identified over 50 years ago, the isolation and characterization of other members of this virus group has been relatively recent. Even so, numerous clinical syndromes have been identified in equid species in association with these viruses. Equid gammaherpesviruses are a genetically heterogeneous viral subfamily, the function of which in host immune modulation and disease pathogenesis has not yet been elucidated. While they share similarities with gammaherpesviruses in humans, the role they play in their relationship with the host is the subject of continued interest and research. Their widespread presence in horses and other equid species provides a considerable challenge in linking them with particular clinical and pathological conditions and in defining their significance from a diagnostic and therapeutic viewpoint. The present review provides an update on the taxonomy, epidemiology, and clinical syndromes, especially respiratory, reported in association with gammaherpesvirus infection in horses, donkeys, and other equid species.Keywords: equid gammaherpesviruses, horses, donkeys, other equid species, equine multinodular pulmonary fibrosisMarenzoni MLStefanetti VDanzetta MLTimoney PJDove Medical PressarticleVeterinary medicineSF600-1100ENVeterinary Medicine: Research and Reports, Vol 2015, Iss default, Pp 91-101 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Veterinary medicine SF600-1100
spellingShingle	Veterinary medicine SF600-1100 Marenzoni ML Stefanetti V Danzetta ML Timoney PJ Gammaherpesvirus infections in equids: a review
description	Maria Luisa Marenzoni,1 Valentina Stefanetti,1 Maria Luisa Danzetta,1 Peter Joseph Timoney21Department of Veterinary Medicine, University of Perugia, Perugia, Italy; 2Department of Veterinary Science, Maxwell H Gluck Equine Research Center, Lexington, KY, USAAbstract: Although the first equine gammaherpesvirus was identified over 50 years ago, the isolation and characterization of other members of this virus group has been relatively recent. Even so, numerous clinical syndromes have been identified in equid species in association with these viruses. Equid gammaherpesviruses are a genetically heterogeneous viral subfamily, the function of which in host immune modulation and disease pathogenesis has not yet been elucidated. While they share similarities with gammaherpesviruses in humans, the role they play in their relationship with the host is the subject of continued interest and research. Their widespread presence in horses and other equid species provides a considerable challenge in linking them with particular clinical and pathological conditions and in defining their significance from a diagnostic and therapeutic viewpoint. The present review provides an update on the taxonomy, epidemiology, and clinical syndromes, especially respiratory, reported in association with gammaherpesvirus infection in horses, donkeys, and other equid species.Keywords: equid gammaherpesviruses, horses, donkeys, other equid species, equine multinodular pulmonary fibrosis
format	article
author	Marenzoni ML Stefanetti V Danzetta ML Timoney PJ
author_facet	Marenzoni ML Stefanetti V Danzetta ML Timoney PJ
author_sort	Marenzoni ML
title	Gammaherpesvirus infections in equids: a review
title_short	Gammaherpesvirus infections in equids: a review
title_full	Gammaherpesvirus infections in equids: a review
title_fullStr	Gammaherpesvirus infections in equids: a review
title_full_unstemmed	Gammaherpesvirus infections in equids: a review
title_sort	gammaherpesvirus infections in equids: a review
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/f848ddfe2823464a9d25acd3d3f079aa
work_keys_str_mv	AT marenzoniml gammaherpesvirusinfectionsinequidsareview AT stefanettiv gammaherpesvirusinfectionsinequidsareview AT danzettaml gammaherpesvirusinfectionsinequidsareview AT timoneypj gammaherpesvirusinfectionsinequidsareview
_version_	1718403232938590208

Gammaherpesvirus infections in equids: a review

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