Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection

Neuronal migration is vital for neuronal circuit morphogenesis and is thought to rely on microtubule-actomyosin crosstalk. Here, the authors use super-resolution imaging and the drebrin microtubule-actin crosslinking protein to show that microtubule-actomyosin coupling controls the direction of cent...

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Autores principales:	Niraj Trivedi, Daniel R. Stabley, Blake Cain, Danielle Howell, Christophe Laumonnerie, Joseph S. Ramahi, Jamshid Temirov, Ryan A. Kerekes, Phillip R. Gordon-Weeks, David J. Solecki
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f84ca427585b4917a3f04e7904711de9
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spelling	oai:doaj.org-article:f84ca427585b4917a3f04e7904711de92021-12-02T15:38:53ZDrebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection10.1038/ncomms144842041-1723https://doaj.org/article/f84ca427585b4917a3f04e7904711de92017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14484https://doaj.org/toc/2041-1723Neuronal migration is vital for neuronal circuit morphogenesis and is thought to rely on microtubule-actomyosin crosstalk. Here, the authors use super-resolution imaging and the drebrin microtubule-actin crosslinking protein to show that microtubule-actomyosin coupling controls the direction of centrosome and somal motility.Niraj TrivediDaniel R. StableyBlake CainDanielle HowellChristophe LaumonnerieJoseph S. RamahiJamshid TemirovRyan A. KerekesPhillip R. Gordon-WeeksDavid J. SoleckiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Niraj Trivedi Daniel R. Stabley Blake Cain Danielle Howell Christophe Laumonnerie Joseph S. Ramahi Jamshid Temirov Ryan A. Kerekes Phillip R. Gordon-Weeks David J. Solecki Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
description	Neuronal migration is vital for neuronal circuit morphogenesis and is thought to rely on microtubule-actomyosin crosstalk. Here, the authors use super-resolution imaging and the drebrin microtubule-actin crosslinking protein to show that microtubule-actomyosin coupling controls the direction of centrosome and somal motility.
format	article
author	Niraj Trivedi Daniel R. Stabley Blake Cain Danielle Howell Christophe Laumonnerie Joseph S. Ramahi Jamshid Temirov Ryan A. Kerekes Phillip R. Gordon-Weeks David J. Solecki
author_facet	Niraj Trivedi Daniel R. Stabley Blake Cain Danielle Howell Christophe Laumonnerie Joseph S. Ramahi Jamshid Temirov Ryan A. Kerekes Phillip R. Gordon-Weeks David J. Solecki
author_sort	Niraj Trivedi
title	Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
title_short	Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
title_full	Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
title_fullStr	Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
title_full_unstemmed	Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
title_sort	drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f84ca427585b4917a3f04e7904711de9
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Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection

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