RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

The Musashi family of RNA binding proteins are found in an oligomeric state in the brains of patients with Alzheimer’s disease. Here the authors show that Mushashi1 and Musashi2 interact with tau protein in patient tissue and in models of tauopathy.

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Autores principales:	Mauro Montalbano, Salome McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Omar D. Johnson, Michael G. Kharas, Rakez Kayed
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af230
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spelling	oai:doaj.org-article:f852a7fca4c646d8bcc24eb27d1af2302021-12-02T15:09:10ZRNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction10.1038/s41467-020-18022-62041-1723https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af2302020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18022-6https://doaj.org/toc/2041-1723The Musashi family of RNA binding proteins are found in an oligomeric state in the brains of patients with Alzheimer’s disease. Here the authors show that Mushashi1 and Musashi2 interact with tau protein in patient tissue and in models of tauopathy.Mauro MontalbanoSalome McAllenNicha PuangmalaiUrmi SenguptaNemil BhattOmar D. JohnsonMichael G. KharasRakez KayedNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mauro Montalbano Salome McAllen Nicha Puangmalai Urmi Sengupta Nemil Bhatt Omar D. Johnson Michael G. Kharas Rakez Kayed RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
description	The Musashi family of RNA binding proteins are found in an oligomeric state in the brains of patients with Alzheimer’s disease. Here the authors show that Mushashi1 and Musashi2 interact with tau protein in patient tissue and in models of tauopathy.
format	article
author	Mauro Montalbano Salome McAllen Nicha Puangmalai Urmi Sengupta Nemil Bhatt Omar D. Johnson Michael G. Kharas Rakez Kayed
author_facet	Mauro Montalbano Salome McAllen Nicha Puangmalai Urmi Sengupta Nemil Bhatt Omar D. Johnson Michael G. Kharas Rakez Kayed
author_sort	Mauro Montalbano
title	RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
title_short	RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
title_full	RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
title_fullStr	RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
title_full_unstemmed	RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
title_sort	rna-binding proteins musashi and tau soluble aggregates initiate nuclear dysfunction
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af230
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RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

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