RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

The Musashi family of RNA binding proteins are found in an oligomeric state in the brains of patients with Alzheimer’s disease. Here the authors show that Mushashi1 and Musashi2 interact with tau protein in patient tissue and in models of tauopathy.

Saved in:
Bibliographic Details
Main Authors: Mauro Montalbano, Salome McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Omar D. Johnson, Michael G. Kharas, Rakez Kayed
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af230
Tags: Add Tag
No Tags, Be the first to tag this record!