Comparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months
Matthew T Hirabayashi,1 Dayeong Lee,1 Joshua T King,1 Samuel Thomsen,1,2 Jella A An1,2 1University of Missouri Columbia School of Medicine, Columbia, MO, USA; 2Department of Ophthalmology, Mason Eye Institute, University of Missouri School of Medicine, Columbia, MO, USACorrespondence: Jella A AnDepa...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2019
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/f85dea9efd9f48048f14cf29caf2e906 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:f85dea9efd9f48048f14cf29caf2e906 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:f85dea9efd9f48048f14cf29caf2e9062021-12-02T06:21:41ZComparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months1177-5483https://doaj.org/article/f85dea9efd9f48048f14cf29caf2e9062019-10-01T00:00:00Zhttps://www.dovepress.com/comparison-of-surgical-outcomes-of-360deg-circumferential-trabeculotom-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Matthew T Hirabayashi,1 Dayeong Lee,1 Joshua T King,1 Samuel Thomsen,1,2 Jella A An1,2 1University of Missouri Columbia School of Medicine, Columbia, MO, USA; 2Department of Ophthalmology, Mason Eye Institute, University of Missouri School of Medicine, Columbia, MO, USACorrespondence: Jella A AnDepartment of Ophthalmology, University of Missouri Columbia, 3215 Wingate Court, Columbia, MO 65201, USATel +1 573 884 1311Fax +1 573 884 3330Email anja@health.missouri.eduPurpose: To compare reductions in intraocular pressure (IOP) and IOP-lowering medication use following sectoral excisional goniotomy with the Kahook Dual Blade (KDB) or 360° trabeculotomy (via either Trab360 or gonioscopy-assisted transluminal trabeculotomy [GATT]) in eyes with open-angle glaucoma (OAG) undergoing phacoemulsification cataract surgery.Methods: A retrospective review was conducted to collect data from adult subjects with early to advanced primary or secondary OAG undergoing phacoemulsification combined with either KDB or 360° trabeculotomy (Trab360 or GATT) between August 1, 2016 and July 30, 2018 for which 6-month follow-up was available. Data collected included IOP, glaucoma medications, adverse events, and additional IOP-lowering procedures. The primary outcome measure was surgical success (≥20% IOP or ≥1 medication reduction without additional IOP-lowering procedures) at 6 months.Results: Data were collected from 74 eyes of 61 subjects undergoing KDB excisional goniotomy and 27 eyes of 25 subjects undergoing 360° trabeculotomy (19 eyes of 17 subjects undergoing Trab360 and 8 eyes of 8 subjects undergoing GATT). At 6 months, 81.7% (58/71) of KDB eyes and 84.6% (22/26) of 360° trabeculotomy eyes achieved surgical successes (P=0.737). Mean IOP reductions and medication reductions were similar between groups at 6 months. However, more eyes undergoing KDB than Trab360/GATT achieved target IOP ≤18 mmHg (80.0% [56/70] vs 59.3% [16/27], P=0.040) and ≤15 mmHg (61.4% [43/70] vs 25.9% [7/27], P=0.003) without further IOP-lowering interventions at 6 months. The nature and frequency of adverse events were similar between groups.Conclusions: Both KDB and Trab360 or GATT procedures similarly lowered both IOP and the need for IOP-lowering medications during the first 6 postoperative months. More eyes undergoing KDB excisional goniotomy than 360° trabeculotomy attained target IOP ≤18 mmHg and ≤15 mmHg at 6 months. A full 360° trabecular bypass may not be necessary to achieve maximal efficacy from this class of micro-invasive glaucoma procedures.Keywords: Kahook Dual Blade, goniotomy, Trab360, GATT, MIGSHirabayashi MTLee DKing JTThomsen SAn JADove Medical PressarticleKahook Dual BladegoniotomyTrab360GATTMIGSOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 2017-2024 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Kahook Dual Blade goniotomy Trab360 GATT MIGS Ophthalmology RE1-994 |
| spellingShingle |
Kahook Dual Blade goniotomy Trab360 GATT MIGS Ophthalmology RE1-994 Hirabayashi MT Lee D King JT Thomsen S An JA Comparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months |
| description |
Matthew T Hirabayashi,1 Dayeong Lee,1 Joshua T King,1 Samuel Thomsen,1,2 Jella A An1,2 1University of Missouri Columbia School of Medicine, Columbia, MO, USA; 2Department of Ophthalmology, Mason Eye Institute, University of Missouri School of Medicine, Columbia, MO, USACorrespondence: Jella A AnDepartment of Ophthalmology, University of Missouri Columbia, 3215 Wingate Court, Columbia, MO 65201, USATel +1 573 884 1311Fax +1 573 884 3330Email anja@health.missouri.eduPurpose: To compare reductions in intraocular pressure (IOP) and IOP-lowering medication use following sectoral excisional goniotomy with the Kahook Dual Blade (KDB) or 360° trabeculotomy (via either Trab360 or gonioscopy-assisted transluminal trabeculotomy [GATT]) in eyes with open-angle glaucoma (OAG) undergoing phacoemulsification cataract surgery.Methods: A retrospective review was conducted to collect data from adult subjects with early to advanced primary or secondary OAG undergoing phacoemulsification combined with either KDB or 360° trabeculotomy (Trab360 or GATT) between August 1, 2016 and July 30, 2018 for which 6-month follow-up was available. Data collected included IOP, glaucoma medications, adverse events, and additional IOP-lowering procedures. The primary outcome measure was surgical success (≥20% IOP or ≥1 medication reduction without additional IOP-lowering procedures) at 6 months.Results: Data were collected from 74 eyes of 61 subjects undergoing KDB excisional goniotomy and 27 eyes of 25 subjects undergoing 360° trabeculotomy (19 eyes of 17 subjects undergoing Trab360 and 8 eyes of 8 subjects undergoing GATT). At 6 months, 81.7% (58/71) of KDB eyes and 84.6% (22/26) of 360° trabeculotomy eyes achieved surgical successes (P=0.737). Mean IOP reductions and medication reductions were similar between groups at 6 months. However, more eyes undergoing KDB than Trab360/GATT achieved target IOP ≤18 mmHg (80.0% [56/70] vs 59.3% [16/27], P=0.040) and ≤15 mmHg (61.4% [43/70] vs 25.9% [7/27], P=0.003) without further IOP-lowering interventions at 6 months. The nature and frequency of adverse events were similar between groups.Conclusions: Both KDB and Trab360 or GATT procedures similarly lowered both IOP and the need for IOP-lowering medications during the first 6 postoperative months. More eyes undergoing KDB excisional goniotomy than 360° trabeculotomy attained target IOP ≤18 mmHg and ≤15 mmHg at 6 months. A full 360° trabecular bypass may not be necessary to achieve maximal efficacy from this class of micro-invasive glaucoma procedures.Keywords: Kahook Dual Blade, goniotomy, Trab360, GATT, MIGS |
| format |
article |
| author |
Hirabayashi MT Lee D King JT Thomsen S An JA |
| author_facet |
Hirabayashi MT Lee D King JT Thomsen S An JA |
| author_sort |
Hirabayashi MT |
| title |
Comparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months |
| title_short |
Comparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months |
| title_full |
Comparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months |
| title_fullStr |
Comparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months |
| title_full_unstemmed |
Comparison Of Surgical Outcomes Of 360° Circumferential Trabeculotomy Versus Sectoral Excisional Goniotomy With The Kahook Dual Blade At 6 Months |
| title_sort |
comparison of surgical outcomes of 360° circumferential trabeculotomy versus sectoral excisional goniotomy with the kahook dual blade at 6 months |
| publisher |
Dove Medical Press |
| publishDate |
2019 |
| url |
https://doaj.org/article/f85dea9efd9f48048f14cf29caf2e906 |
| work_keys_str_mv |
AT hirabayashimt comparisonofsurgicaloutcomesof360degcircumferentialtrabeculotomyversussectoralexcisionalgoniotomywiththekahookdualbladeat6months AT leed comparisonofsurgicaloutcomesof360degcircumferentialtrabeculotomyversussectoralexcisionalgoniotomywiththekahookdualbladeat6months AT kingjt comparisonofsurgicaloutcomesof360degcircumferentialtrabeculotomyversussectoralexcisionalgoniotomywiththekahookdualbladeat6months AT thomsens comparisonofsurgicaloutcomesof360degcircumferentialtrabeculotomyversussectoralexcisionalgoniotomywiththekahookdualbladeat6months AT anja comparisonofsurgicaloutcomesof360degcircumferentialtrabeculotomyversussectoralexcisionalgoniotomywiththekahookdualbladeat6months |
| _version_ |
1718399969893810176 |