Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis

Gene isoforms result from variable transcription start sites (TSSs) and polyadenylation sites (PASs) at the end of transcripts. Here, the authors perform transcript isoform sequencing and find widespread promoter- proximal transcriptional termination in Arabidopsis, suggesting this may represent a c...

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Autores principales: Quentin Angelo Thomas, Ryan Ard, Jinghan Liu, Bingnan Li, Jingwen Wang, Vicent Pelechano, Sebastian Marquardt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f860803bf67f41868327ca68ff68389d
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spelling oai:doaj.org-article:f860803bf67f41868327ca68ff68389d2021-12-02T15:45:19ZTranscript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis10.1038/s41467-020-16390-72041-1723https://doaj.org/article/f860803bf67f41868327ca68ff68389d2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16390-7https://doaj.org/toc/2041-1723Gene isoforms result from variable transcription start sites (TSSs) and polyadenylation sites (PASs) at the end of transcripts. Here, the authors perform transcript isoform sequencing and find widespread promoter- proximal transcriptional termination in Arabidopsis, suggesting this may represent a checkpoint that regulates plant gene expression.Quentin Angelo ThomasRyan ArdJinghan LiuBingnan LiJingwen WangVicent PelechanoSebastian MarquardtNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Quentin Angelo Thomas
Ryan Ard
Jinghan Liu
Bingnan Li
Jingwen Wang
Vicent Pelechano
Sebastian Marquardt
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis
description Gene isoforms result from variable transcription start sites (TSSs) and polyadenylation sites (PASs) at the end of transcripts. Here, the authors perform transcript isoform sequencing and find widespread promoter- proximal transcriptional termination in Arabidopsis, suggesting this may represent a checkpoint that regulates plant gene expression.
format article
author Quentin Angelo Thomas
Ryan Ard
Jinghan Liu
Bingnan Li
Jingwen Wang
Vicent Pelechano
Sebastian Marquardt
author_facet Quentin Angelo Thomas
Ryan Ard
Jinghan Liu
Bingnan Li
Jingwen Wang
Vicent Pelechano
Sebastian Marquardt
author_sort Quentin Angelo Thomas
title Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis
title_short Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis
title_full Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis
title_fullStr Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis
title_full_unstemmed Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis
title_sort transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in arabidopsis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f860803bf67f41868327ca68ff68389d
work_keys_str_mv AT quentinangelothomas transcriptisoformsequencingrevealswidespreadpromoterproximaltranscriptionalterminationinarabidopsis
AT ryanard transcriptisoformsequencingrevealswidespreadpromoterproximaltranscriptionalterminationinarabidopsis
AT jinghanliu transcriptisoformsequencingrevealswidespreadpromoterproximaltranscriptionalterminationinarabidopsis
AT bingnanli transcriptisoformsequencingrevealswidespreadpromoterproximaltranscriptionalterminationinarabidopsis
AT jingwenwang transcriptisoformsequencingrevealswidespreadpromoterproximaltranscriptionalterminationinarabidopsis
AT vicentpelechano transcriptisoformsequencingrevealswidespreadpromoterproximaltranscriptionalterminationinarabidopsis
AT sebastianmarquardt transcriptisoformsequencingrevealswidespreadpromoterproximaltranscriptionalterminationinarabidopsis
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