Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid

Local pH alterations can be manifestations of pathologies such as cancer, inflammation and ischaemia. Here Düwelet al. show hyperpolarized 13C-labelled zymonic acid can be used as a non-invasive probe to map and measure pH in vivo, suggesting it as a candidate for clinical imaging and a diagnostic t...

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Autores principales:	Stephan Düwel, Christian Hundshammer, Malte Gersch, Benedikt Feuerecker, Katja Steiger, Achim Buck, Axel Walch, Axel Haase, Steffen J. Glaser, Markus Schwaiger, Franz Schilling
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f865be0858b84adf81315a399aa1c815
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spelling	oai:doaj.org-article:f865be0858b84adf81315a399aa1c8152021-12-02T17:01:23ZImaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid10.1038/ncomms151262041-1723https://doaj.org/article/f865be0858b84adf81315a399aa1c8152017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15126https://doaj.org/toc/2041-1723Local pH alterations can be manifestations of pathologies such as cancer, inflammation and ischaemia. Here Düwelet al. show hyperpolarized 13C-labelled zymonic acid can be used as a non-invasive probe to map and measure pH in vivo, suggesting it as a candidate for clinical imaging and a diagnostic tool.Stephan DüwelChristian HundshammerMalte GerschBenedikt FeuereckerKatja SteigerAchim BuckAxel WalchAxel HaaseSteffen J. GlaserMarkus SchwaigerFranz SchillingNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephan Düwel Christian Hundshammer Malte Gersch Benedikt Feuerecker Katja Steiger Achim Buck Axel Walch Axel Haase Steffen J. Glaser Markus Schwaiger Franz Schilling Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid
description	Local pH alterations can be manifestations of pathologies such as cancer, inflammation and ischaemia. Here Düwelet al. show hyperpolarized 13C-labelled zymonic acid can be used as a non-invasive probe to map and measure pH in vivo, suggesting it as a candidate for clinical imaging and a diagnostic tool.
format	article
author	Stephan Düwel Christian Hundshammer Malte Gersch Benedikt Feuerecker Katja Steiger Achim Buck Axel Walch Axel Haase Steffen J. Glaser Markus Schwaiger Franz Schilling
author_facet	Stephan Düwel Christian Hundshammer Malte Gersch Benedikt Feuerecker Katja Steiger Achim Buck Axel Walch Axel Haase Steffen J. Glaser Markus Schwaiger Franz Schilling
author_sort	Stephan Düwel
title	Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid
title_short	Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid
title_full	Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid
title_fullStr	Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid
title_full_unstemmed	Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid
title_sort	imaging of ph in vivo using hyperpolarized 13c-labelled zymonic acid
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f865be0858b84adf81315a399aa1c815
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Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid

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