Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate

Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate

Abstract Helicobacter pylori cagA-positive strains are critically involved in the development of gastric cancer. Upon delivery into gastric epithelial cells via type IV secretion, the cagA-encoded CagA interacts with and thereby perturbs the pro-oncogenic phosphatase SHP2 and the polarity-regulating...

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Autores principales: Kana Hashi, Chihiro Imai, Koji Yahara, Kamrunnesa Tahmina, Takeru Hayashi, Takeshi Azuma, Takako Miyabe-Nishiwaki, Hideyuki Sato, Masao Matsuoka, Sachi Niimi, Munehiro Okamoto, Masanori Hatakeyama
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Pylori cagA-positive Strains
Western CagA
Organoid
CagA Protein
East Asian CagA
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/f8666df3919444ac8c305271f76849db
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https://doaj.org/article/f8666df3919444ac8c305271f76849db

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