Rhino-orbito-cerebral Mucormycosis: Pictorial Review
Abstract Mucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-1...
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oai:doaj.org-article:f86b68ae0142403480caae07086c77392021-11-14T12:10:51ZRhino-orbito-cerebral Mucormycosis: Pictorial Review10.1186/s13244-021-01109-z1869-4101https://doaj.org/article/f86b68ae0142403480caae07086c77392021-11-01T00:00:00Zhttps://doi.org/10.1186/s13244-021-01109-zhttps://doaj.org/toc/1869-4101Abstract Mucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-19 disease owing to a complex interplay of metabolic factors and corticosteroid therapy. Rhino-orbito-cerebral mucormycosis (ROCM) is the most common clinical form of MCR infection and refers to infection of the nasal cavities, paranasal sinuses, neck spaces, orbits and intracranial structures. Sinonasal inoculation is typically the primary site of infection; the necrotising and angioinvasive properties of the fungus facilitate its spread into adjacent structures. In this review, we discuss the pertinent mycology and risk factors of MCR infection. The review also aims to acquaint the reader with the cross-sectional imaging appearances of ROCM and its complications. All the cases discussed in this pictorial essay are microbiologically and/or histopathologically proven cases of ROCM with concomitant COVID-19 infection.Vivek PaiRima SansiRitesh KharcheSridevi Chaitanya BandiliBhujang PaiSpringerOpenarticleMucormycosisRhino-orbito-cerebral MucormycosisInvasive fungal sinusitisMedical physics. Medical radiology. Nuclear medicineR895-920ENInsights into Imaging, Vol 12, Iss 1, Pp 1-17 (2021) |
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Mucormycosis Rhino-orbito-cerebral Mucormycosis Invasive fungal sinusitis Medical physics. Medical radiology. Nuclear medicine R895-920 |
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Mucormycosis Rhino-orbito-cerebral Mucormycosis Invasive fungal sinusitis Medical physics. Medical radiology. Nuclear medicine R895-920 Vivek Pai Rima Sansi Ritesh Kharche Sridevi Chaitanya Bandili Bhujang Pai Rhino-orbito-cerebral Mucormycosis: Pictorial Review |
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Abstract Mucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-19 disease owing to a complex interplay of metabolic factors and corticosteroid therapy. Rhino-orbito-cerebral mucormycosis (ROCM) is the most common clinical form of MCR infection and refers to infection of the nasal cavities, paranasal sinuses, neck spaces, orbits and intracranial structures. Sinonasal inoculation is typically the primary site of infection; the necrotising and angioinvasive properties of the fungus facilitate its spread into adjacent structures. In this review, we discuss the pertinent mycology and risk factors of MCR infection. The review also aims to acquaint the reader with the cross-sectional imaging appearances of ROCM and its complications. All the cases discussed in this pictorial essay are microbiologically and/or histopathologically proven cases of ROCM with concomitant COVID-19 infection. |
format |
article |
author |
Vivek Pai Rima Sansi Ritesh Kharche Sridevi Chaitanya Bandili Bhujang Pai |
author_facet |
Vivek Pai Rima Sansi Ritesh Kharche Sridevi Chaitanya Bandili Bhujang Pai |
author_sort |
Vivek Pai |
title |
Rhino-orbito-cerebral Mucormycosis: Pictorial Review |
title_short |
Rhino-orbito-cerebral Mucormycosis: Pictorial Review |
title_full |
Rhino-orbito-cerebral Mucormycosis: Pictorial Review |
title_fullStr |
Rhino-orbito-cerebral Mucormycosis: Pictorial Review |
title_full_unstemmed |
Rhino-orbito-cerebral Mucormycosis: Pictorial Review |
title_sort |
rhino-orbito-cerebral mucormycosis: pictorial review |
publisher |
SpringerOpen |
publishDate |
2021 |
url |
https://doaj.org/article/f86b68ae0142403480caae07086c7739 |
work_keys_str_mv |
AT vivekpai rhinoorbitocerebralmucormycosispictorialreview AT rimasansi rhinoorbitocerebralmucormycosispictorialreview AT riteshkharche rhinoorbitocerebralmucormycosispictorialreview AT sridevichaitanyabandili rhinoorbitocerebralmucormycosispictorialreview AT bhujangpai rhinoorbitocerebralmucormycosispictorialreview |
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1718429442840199168 |