Rhino-orbito-cerebral Mucormycosis: Pictorial Review

Abstract Mucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-1...

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Autores principales: Vivek Pai, Rima Sansi, Ritesh Kharche, Sridevi Chaitanya Bandili, Bhujang Pai
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Lenguaje:EN
Publicado: SpringerOpen 2021
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Acceso en línea:https://doaj.org/article/f86b68ae0142403480caae07086c7739
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spelling oai:doaj.org-article:f86b68ae0142403480caae07086c77392021-11-14T12:10:51ZRhino-orbito-cerebral Mucormycosis: Pictorial Review10.1186/s13244-021-01109-z1869-4101https://doaj.org/article/f86b68ae0142403480caae07086c77392021-11-01T00:00:00Zhttps://doi.org/10.1186/s13244-021-01109-zhttps://doaj.org/toc/1869-4101Abstract Mucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-19 disease owing to a complex interplay of metabolic factors and corticosteroid therapy. Rhino-orbito-cerebral mucormycosis (ROCM) is the most common clinical form of MCR infection and refers to infection of the nasal cavities, paranasal sinuses, neck spaces, orbits and intracranial structures. Sinonasal inoculation is typically the primary site of infection; the necrotising and angioinvasive properties of the fungus facilitate its spread into adjacent structures. In this review, we discuss the pertinent mycology and risk factors of MCR infection. The review also aims to acquaint the reader with the cross-sectional imaging appearances of ROCM and its complications. All the cases discussed in this pictorial essay are microbiologically and/or histopathologically proven cases of ROCM with concomitant COVID-19 infection.Vivek PaiRima SansiRitesh KharcheSridevi Chaitanya BandiliBhujang PaiSpringerOpenarticleMucormycosisRhino-orbito-cerebral MucormycosisInvasive fungal sinusitisMedical physics. Medical radiology. Nuclear medicineR895-920ENInsights into Imaging, Vol 12, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Mucormycosis
Rhino-orbito-cerebral Mucormycosis
Invasive fungal sinusitis
Medical physics. Medical radiology. Nuclear medicine
R895-920
spellingShingle Mucormycosis
Rhino-orbito-cerebral Mucormycosis
Invasive fungal sinusitis
Medical physics. Medical radiology. Nuclear medicine
R895-920
Vivek Pai
Rima Sansi
Ritesh Kharche
Sridevi Chaitanya Bandili
Bhujang Pai
Rhino-orbito-cerebral Mucormycosis: Pictorial Review
description Abstract Mucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-19 disease owing to a complex interplay of metabolic factors and corticosteroid therapy. Rhino-orbito-cerebral mucormycosis (ROCM) is the most common clinical form of MCR infection and refers to infection of the nasal cavities, paranasal sinuses, neck spaces, orbits and intracranial structures. Sinonasal inoculation is typically the primary site of infection; the necrotising and angioinvasive properties of the fungus facilitate its spread into adjacent structures. In this review, we discuss the pertinent mycology and risk factors of MCR infection. The review also aims to acquaint the reader with the cross-sectional imaging appearances of ROCM and its complications. All the cases discussed in this pictorial essay are microbiologically and/or histopathologically proven cases of ROCM with concomitant COVID-19 infection.
format article
author Vivek Pai
Rima Sansi
Ritesh Kharche
Sridevi Chaitanya Bandili
Bhujang Pai
author_facet Vivek Pai
Rima Sansi
Ritesh Kharche
Sridevi Chaitanya Bandili
Bhujang Pai
author_sort Vivek Pai
title Rhino-orbito-cerebral Mucormycosis: Pictorial Review
title_short Rhino-orbito-cerebral Mucormycosis: Pictorial Review
title_full Rhino-orbito-cerebral Mucormycosis: Pictorial Review
title_fullStr Rhino-orbito-cerebral Mucormycosis: Pictorial Review
title_full_unstemmed Rhino-orbito-cerebral Mucormycosis: Pictorial Review
title_sort rhino-orbito-cerebral mucormycosis: pictorial review
publisher SpringerOpen
publishDate 2021
url https://doaj.org/article/f86b68ae0142403480caae07086c7739
work_keys_str_mv AT vivekpai rhinoorbitocerebralmucormycosispictorialreview
AT rimasansi rhinoorbitocerebralmucormycosispictorialreview
AT riteshkharche rhinoorbitocerebralmucormycosispictorialreview
AT sridevichaitanyabandili rhinoorbitocerebralmucormycosispictorialreview
AT bhujangpai rhinoorbitocerebralmucormycosispictorialreview
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