Darapladib inhibits atherosclerosis development in type 2 diabetes mellitus Sprague-Dawley rat model
Objective. Increase in the low-density lipoprotein (LDL) level in diabetes mellitus and atherosclerosis is related to lipoprotein associated phospholipase A2 (Lp-PLA2). Lp-PLA2 is an enzyme that produces lysophosphatidylcholine (LysoPC) and oxidized nonesterified fatty acids (oxNEFA). LysoPC regulat...
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Main Authors: | Wihastuti Titin Andri, Heriansyah Teuku, Hanifa Hanifa, Andarini Sri, Sholichah Zuhrotus, Sulfia Yuni Hendrati, Adam Aditya Angela, Refialdinata Jeki, Lutfiana Nurul Cholifah |
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Format: | article |
Language: | EN |
Published: |
Sciendo
2018
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Online Access: | https://doaj.org/article/f86c69e1ff364b888452bae779ae9e01 |
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