Darapladib inhibits atherosclerosis development in type 2 diabetes mellitus Sprague-Dawley rat model
Objective. Increase in the low-density lipoprotein (LDL) level in diabetes mellitus and atherosclerosis is related to lipoprotein associated phospholipase A2 (Lp-PLA2). Lp-PLA2 is an enzyme that produces lysophosphatidylcholine (LysoPC) and oxidized nonesterified fatty acids (oxNEFA). LysoPC regulat...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Sciendo
2018
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| Accès en ligne: | https://doaj.org/article/f86c69e1ff364b888452bae779ae9e01 |
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