Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection

Identification of host factors associated with severe influenza infection could provide insights into treatment options. Here, the authors provide transcriptomic analyses of blood from >100 influenza infected patients and show that changes in circulating neutrophils are associated with severe inf...

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Autores principales: Benjamin M. Tang, Maryam Shojaei, Sally Teoh, Adrienne Meyers, John Ho, T. Blake Ball, Yoav Keynan, Amarnath Pisipati, Aseem Kumar, Damon P. Eisen, Kevin Lai, Mark Gillett, Rahul Santram, Robert Geffers, Jens Schreiber, Khyobeni Mozhui, Stephen Huang, Grant P. Parnell, Marek Nalos, Monika Holubova, Tracy Chew, David Booth, Anand Kumar, Anthony McLean, Klaus Schughart
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f8717f61b4914b2fa628be04cd6755a4
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Sumario:Identification of host factors associated with severe influenza infection could provide insights into treatment options. Here, the authors provide transcriptomic analyses of blood from >100 influenza infected patients and show that changes in circulating neutrophils are associated with severe influenza infection.