Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection
Identification of host factors associated with severe influenza infection could provide insights into treatment options. Here, the authors provide transcriptomic analyses of blood from >100 influenza infected patients and show that changes in circulating neutrophils are associated with severe inf...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2019
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/f8717f61b4914b2fa628be04cd6755a4 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:f8717f61b4914b2fa628be04cd6755a4 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:f8717f61b4914b2fa628be04cd6755a42021-12-02T16:58:13ZNeutrophils-related host factors associated with severe disease and fatality in patients with influenza infection10.1038/s41467-019-11249-y2041-1723https://doaj.org/article/f8717f61b4914b2fa628be04cd6755a42019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11249-yhttps://doaj.org/toc/2041-1723Identification of host factors associated with severe influenza infection could provide insights into treatment options. Here, the authors provide transcriptomic analyses of blood from >100 influenza infected patients and show that changes in circulating neutrophils are associated with severe influenza infection.Benjamin M. TangMaryam ShojaeiSally TeohAdrienne MeyersJohn HoT. Blake BallYoav KeynanAmarnath PisipatiAseem KumarDamon P. EisenKevin LaiMark GillettRahul SantramRobert GeffersJens SchreiberKhyobeni MozhuiStephen HuangGrant P. ParnellMarek NalosMonika HolubovaTracy ChewDavid BoothAnand KumarAnthony McLeanKlaus SchughartNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Benjamin M. Tang Maryam Shojaei Sally Teoh Adrienne Meyers John Ho T. Blake Ball Yoav Keynan Amarnath Pisipati Aseem Kumar Damon P. Eisen Kevin Lai Mark Gillett Rahul Santram Robert Geffers Jens Schreiber Khyobeni Mozhui Stephen Huang Grant P. Parnell Marek Nalos Monika Holubova Tracy Chew David Booth Anand Kumar Anthony McLean Klaus Schughart Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection |
| description |
Identification of host factors associated with severe influenza infection could provide insights into treatment options. Here, the authors provide transcriptomic analyses of blood from >100 influenza infected patients and show that changes in circulating neutrophils are associated with severe influenza infection. |
| format |
article |
| author |
Benjamin M. Tang Maryam Shojaei Sally Teoh Adrienne Meyers John Ho T. Blake Ball Yoav Keynan Amarnath Pisipati Aseem Kumar Damon P. Eisen Kevin Lai Mark Gillett Rahul Santram Robert Geffers Jens Schreiber Khyobeni Mozhui Stephen Huang Grant P. Parnell Marek Nalos Monika Holubova Tracy Chew David Booth Anand Kumar Anthony McLean Klaus Schughart |
| author_facet |
Benjamin M. Tang Maryam Shojaei Sally Teoh Adrienne Meyers John Ho T. Blake Ball Yoav Keynan Amarnath Pisipati Aseem Kumar Damon P. Eisen Kevin Lai Mark Gillett Rahul Santram Robert Geffers Jens Schreiber Khyobeni Mozhui Stephen Huang Grant P. Parnell Marek Nalos Monika Holubova Tracy Chew David Booth Anand Kumar Anthony McLean Klaus Schughart |
| author_sort |
Benjamin M. Tang |
| title |
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection |
| title_short |
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection |
| title_full |
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection |
| title_fullStr |
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection |
| title_full_unstemmed |
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection |
| title_sort |
neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/f8717f61b4914b2fa628be04cd6755a4 |
| work_keys_str_mv |
AT benjaminmtang neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT maryamshojaei neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT sallyteoh neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT adriennemeyers neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT johnho neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT tblakeball neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT yoavkeynan neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT amarnathpisipati neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT aseemkumar neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT damonpeisen neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT kevinlai neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT markgillett neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT rahulsantram neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT robertgeffers neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT jensschreiber neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT khyobenimozhui neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT stephenhuang neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT grantpparnell neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT mareknalos neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT monikaholubova neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT tracychew neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT davidbooth neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT anandkumar neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT anthonymclean neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection AT klausschughart neutrophilsrelatedhostfactorsassociatedwithseverediseaseandfatalityinpatientswithinfluenzainfection |
| _version_ |
1718382424282365952 |