Mouse embryo geometry drives formation of robust signaling gradients through receptor localization

How receptor localization affects morphogen gradient formation during embryonic development is unclear. Here, the authors study the relationship between the BMP gradient, receptor localization, and compartmentalized geometry in the early mouse embryo, using experimental data and computational simula...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Zhechun Zhang, Steven Zwick, Ethan Loew, Joshua S. Grimley, Sharad Ramanathan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f874512482c64daeb7813952838f77f6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f874512482c64daeb7813952838f77f6
record_format	dspace
spelling	oai:doaj.org-article:f874512482c64daeb7813952838f77f62021-12-02T15:36:05ZMouse embryo geometry drives formation of robust signaling gradients through receptor localization10.1038/s41467-019-12533-72041-1723https://doaj.org/article/f874512482c64daeb7813952838f77f62019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12533-7https://doaj.org/toc/2041-1723How receptor localization affects morphogen gradient formation during embryonic development is unclear. Here, the authors study the relationship between the BMP gradient, receptor localization, and compartmentalized geometry in the early mouse embryo, using experimental data and computational simulation.Zhechun ZhangSteven ZwickEthan LoewJoshua S. GrimleySharad RamanathanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhechun Zhang Steven Zwick Ethan Loew Joshua S. Grimley Sharad Ramanathan Mouse embryo geometry drives formation of robust signaling gradients through receptor localization
description	How receptor localization affects morphogen gradient formation during embryonic development is unclear. Here, the authors study the relationship between the BMP gradient, receptor localization, and compartmentalized geometry in the early mouse embryo, using experimental data and computational simulation.
format	article
author	Zhechun Zhang Steven Zwick Ethan Loew Joshua S. Grimley Sharad Ramanathan
author_facet	Zhechun Zhang Steven Zwick Ethan Loew Joshua S. Grimley Sharad Ramanathan
author_sort	Zhechun Zhang
title	Mouse embryo geometry drives formation of robust signaling gradients through receptor localization
title_short	Mouse embryo geometry drives formation of robust signaling gradients through receptor localization
title_full	Mouse embryo geometry drives formation of robust signaling gradients through receptor localization
title_fullStr	Mouse embryo geometry drives formation of robust signaling gradients through receptor localization
title_full_unstemmed	Mouse embryo geometry drives formation of robust signaling gradients through receptor localization
title_sort	mouse embryo geometry drives formation of robust signaling gradients through receptor localization
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f874512482c64daeb7813952838f77f6
work_keys_str_mv	AT zhechunzhang mouseembryogeometrydrivesformationofrobustsignalinggradientsthroughreceptorlocalization AT stevenzwick mouseembryogeometrydrivesformationofrobustsignalinggradientsthroughreceptorlocalization AT ethanloew mouseembryogeometrydrivesformationofrobustsignalinggradientsthroughreceptorlocalization AT joshuasgrimley mouseembryogeometrydrivesformationofrobustsignalinggradientsthroughreceptorlocalization AT sharadramanathan mouseembryogeometrydrivesformationofrobustsignalinggradientsthroughreceptorlocalization
_version_	1718386390190784512

Mouse embryo geometry drives formation of robust signaling gradients through receptor localization

Ejemplares similares