Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16

Visceral adiposity is associated with metabolic diseases, whereas subcutaneous adiposity is comparatively benign. Here, the authors report that subcutaneous adipose tissue adopts visceral-like characteristics in response to prolonged fasting, and show this is mediated by miR-149-3p and its target, P...

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Autores principales:	Hanying Ding, Shasha Zheng, Daniel Garcia-Ruiz, Dongxia Hou, Zhe Wei, Zhicong Liao, Limin Li, Yujing Zhang, Xiao Han, Ke Zen, Chen-Yu Zhang, Jing Li, Xiaohong Jiang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f877f6cf92a7471b819414666df8c0fe
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spelling	oai:doaj.org-article:f877f6cf92a7471b819414666df8c0fe2021-12-02T16:57:01ZFasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM1610.1038/ncomms115332041-1723https://doaj.org/article/f877f6cf92a7471b819414666df8c0fe2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11533https://doaj.org/toc/2041-1723Visceral adiposity is associated with metabolic diseases, whereas subcutaneous adiposity is comparatively benign. Here, the authors report that subcutaneous adipose tissue adopts visceral-like characteristics in response to prolonged fasting, and show this is mediated by miR-149-3p and its target, PRDM16.Hanying DingShasha ZhengDaniel Garcia-RuizDongxia HouZhe WeiZhicong LiaoLimin LiYujing ZhangXiao HanKe ZenChen-Yu ZhangJing LiXiaohong JiangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hanying Ding Shasha Zheng Daniel Garcia-Ruiz Dongxia Hou Zhe Wei Zhicong Liao Limin Li Yujing Zhang Xiao Han Ke Zen Chen-Yu Zhang Jing Li Xiaohong Jiang Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16
description	Visceral adiposity is associated with metabolic diseases, whereas subcutaneous adiposity is comparatively benign. Here, the authors report that subcutaneous adipose tissue adopts visceral-like characteristics in response to prolonged fasting, and show this is mediated by miR-149-3p and its target, PRDM16.
format	article
author	Hanying Ding Shasha Zheng Daniel Garcia-Ruiz Dongxia Hou Zhe Wei Zhicong Liao Limin Li Yujing Zhang Xiao Han Ke Zen Chen-Yu Zhang Jing Li Xiaohong Jiang
author_facet	Hanying Ding Shasha Zheng Daniel Garcia-Ruiz Dongxia Hou Zhe Wei Zhicong Liao Limin Li Yujing Zhang Xiao Han Ke Zen Chen-Yu Zhang Jing Li Xiaohong Jiang
author_sort	Hanying Ding
title	Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16
title_short	Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16
title_full	Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16
title_fullStr	Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16
title_full_unstemmed	Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16
title_sort	fasting induces a subcutaneous-to-visceral fat switch mediated by microrna-149-3p and suppression of prdm16
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f877f6cf92a7471b819414666df8c0fe
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Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16

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