Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity

Gs-coupled receptor signaling is well known to modulate adipocyte metabolism, but the role of Gi-coupled receptors in adipose tissue is less well understood. Here the authors show that signaling via Gi-type G proteins expressed by adipocytes is essential for maintaining proper blood glucose homeosta...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lei Wang, Sai P. Pydi, Lu Zhu, Luiz F. Barella, Yinghong Cui, Oksana Gavrilova, Kendra K. Bence, Cecile Vernochet, Jürgen Wess
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f883d39ac98a4be2a5e5616bc15a5843
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f883d39ac98a4be2a5e5616bc15a5843
record_format	dspace
spelling	oai:doaj.org-article:f883d39ac98a4be2a5e5616bc15a58432021-12-02T17:47:34ZAdipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity10.1038/s41467-020-16756-x2041-1723https://doaj.org/article/f883d39ac98a4be2a5e5616bc15a58432020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16756-xhttps://doaj.org/toc/2041-1723Gs-coupled receptor signaling is well known to modulate adipocyte metabolism, but the role of Gi-coupled receptors in adipose tissue is less well understood. Here the authors show that signaling via Gi-type G proteins expressed by adipocytes is essential for maintaining proper blood glucose homeostasis.Lei WangSai P. PydiLu ZhuLuiz F. BarellaYinghong CuiOksana GavrilovaKendra K. BenceCecile VernochetJürgen WessNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lei Wang Sai P. Pydi Lu Zhu Luiz F. Barella Yinghong Cui Oksana Gavrilova Kendra K. Bence Cecile Vernochet Jürgen Wess Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
description	Gs-coupled receptor signaling is well known to modulate adipocyte metabolism, but the role of Gi-coupled receptors in adipose tissue is less well understood. Here the authors show that signaling via Gi-type G proteins expressed by adipocytes is essential for maintaining proper blood glucose homeostasis.
format	article
author	Lei Wang Sai P. Pydi Lu Zhu Luiz F. Barella Yinghong Cui Oksana Gavrilova Kendra K. Bence Cecile Vernochet Jürgen Wess
author_facet	Lei Wang Sai P. Pydi Lu Zhu Luiz F. Barella Yinghong Cui Oksana Gavrilova Kendra K. Bence Cecile Vernochet Jürgen Wess
author_sort	Lei Wang
title	Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
title_short	Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
title_full	Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
title_fullStr	Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
title_full_unstemmed	Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
title_sort	adipocyte gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f883d39ac98a4be2a5e5616bc15a5843
work_keys_str_mv	AT leiwang adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT saippydi adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT luzhu adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT luizfbarella adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT yinghongcui adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT oksanagavrilova adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT kendrakbence adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT cecilevernochet adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity AT jurgenwess adipocytegisignalingisessentialformaintainingwholebodyglucosehomeostasisandinsulinsensitivity
_version_	1718379505048879104

Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity

Ejemplares similares