COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY

Objective: To compare lipid profile in patients with diabetic neuropathy and without neuropathy. Study Design: Cross-sectional comparative study. Place and Duration of Study: This study was carried out at Multidisciplinary Lab-1, Department of Biochemistry and Molecular Biology, Army Medical C...

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Autores principales: Kanwal Huma, Khadija Mehboob, Amir Rashid, Fatima Fuad, Muhammad Mamoon Mujahid, Asma Arshad
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2021
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Acceso en línea:https://doi.org/10.51253/pafmj.v71iSuppl-1.5484
https://doaj.org/article/f8911171b25140a9af85b6b766020c1c
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spelling oai:doaj.org-article:f8911171b25140a9af85b6b766020c1c2021-12-02T17:18:43ZCOMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDYhttps://doi.org/10.51253/pafmj.v71iSuppl-1.54840030-96482411-8842https://doaj.org/article/f8911171b25140a9af85b6b766020c1c2021-01-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5484https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare lipid profile in patients with diabetic neuropathy and without neuropathy. Study Design: Cross-sectional comparative study. Place and Duration of Study: This study was carried out at Multidisciplinary Lab-1, Department of Biochemistry and Molecular Biology, Army Medical College, from Jan 2020 to Sep 2020 in collaboration with Pak-Emirates Military Hospital, Rawalpindi. Methodology: Eighty-four subjects were selected and divided into three groups, twenty-eight in each. Group I included diagnosed patients with type 2 diabetes mellitus with peripheral neuropathy, group II included diagnosed patients with type 2 diabetes mellitus without peripheral neuropathy and group III consisted of healthy individuals. Biochemical parameters including total cholesterol, triglycerides, high density lipoprotein cholesterol and low density lipoprotein cholesterol were measured. Data was analyzed by SPSS version 22.0. One way ANOVA test was used that followed by post-Hoc Tukey test for group comparison. Results: There was significant difference in triglycerides (p-value 0.001) and high density lipoprotein cholesterol (0.003) levels among group I and III. While, between group II and III significant difference of high density lipoprotein cholesterol was present. There was no significant difference between group I and II regarding all lipid profile parameters. Conclusion: There was significant increase of triglycerides levels and decrease of high density lipoprotein cholesterol in patients with diabetic peripheral neuropathy as compared to healthy controls. No significant difference was observed for all parameters of lipid profile between patients with diabetic peripheral neuropathy and without peripheral neuropathy.Kanwal HumaKhadija MehboobAmir RashidFatima FuadMuhammad Mamoon MujahidAsma ArshadArmy Medical College Rawalpindiarticlediabetic peripheral neuropathylipid profiletype 2 diabetes mellitusMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss SUPPL-1, Pp 202-206 (2021)
institution DOAJ
collection DOAJ
language EN
topic diabetic peripheral neuropathy
lipid profile
type 2 diabetes mellitus
Medicine
R
Medicine (General)
R5-920
spellingShingle diabetic peripheral neuropathy
lipid profile
type 2 diabetes mellitus
Medicine
R
Medicine (General)
R5-920
Kanwal Huma
Khadija Mehboob
Amir Rashid
Fatima Fuad
Muhammad Mamoon Mujahid
Asma Arshad
COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY
description Objective: To compare lipid profile in patients with diabetic neuropathy and without neuropathy. Study Design: Cross-sectional comparative study. Place and Duration of Study: This study was carried out at Multidisciplinary Lab-1, Department of Biochemistry and Molecular Biology, Army Medical College, from Jan 2020 to Sep 2020 in collaboration with Pak-Emirates Military Hospital, Rawalpindi. Methodology: Eighty-four subjects were selected and divided into three groups, twenty-eight in each. Group I included diagnosed patients with type 2 diabetes mellitus with peripheral neuropathy, group II included diagnosed patients with type 2 diabetes mellitus without peripheral neuropathy and group III consisted of healthy individuals. Biochemical parameters including total cholesterol, triglycerides, high density lipoprotein cholesterol and low density lipoprotein cholesterol were measured. Data was analyzed by SPSS version 22.0. One way ANOVA test was used that followed by post-Hoc Tukey test for group comparison. Results: There was significant difference in triglycerides (p-value 0.001) and high density lipoprotein cholesterol (0.003) levels among group I and III. While, between group II and III significant difference of high density lipoprotein cholesterol was present. There was no significant difference between group I and II regarding all lipid profile parameters. Conclusion: There was significant increase of triglycerides levels and decrease of high density lipoprotein cholesterol in patients with diabetic peripheral neuropathy as compared to healthy controls. No significant difference was observed for all parameters of lipid profile between patients with diabetic peripheral neuropathy and without peripheral neuropathy.
format article
author Kanwal Huma
Khadija Mehboob
Amir Rashid
Fatima Fuad
Muhammad Mamoon Mujahid
Asma Arshad
author_facet Kanwal Huma
Khadija Mehboob
Amir Rashid
Fatima Fuad
Muhammad Mamoon Mujahid
Asma Arshad
author_sort Kanwal Huma
title COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY
title_short COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY
title_full COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY
title_fullStr COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY
title_full_unstemmed COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY
title_sort comparison of lipid profile in patients with diabetic neuropathy and without neuropathy; a cross sectional study
publisher Army Medical College Rawalpindi
publishDate 2021
url https://doi.org/10.51253/pafmj.v71iSuppl-1.5484
https://doaj.org/article/f8911171b25140a9af85b6b766020c1c
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