COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY
Objective: To compare lipid profile in patients with diabetic neuropathy and without neuropathy. Study Design: Cross-sectional comparative study. Place and Duration of Study: This study was carried out at Multidisciplinary Lab-1, Department of Biochemistry and Molecular Biology, Army Medical C...
Guardado en:
Autores principales: | , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Army Medical College Rawalpindi
2021
|
Materias: | |
Acceso en línea: | https://doi.org/10.51253/pafmj.v71iSuppl-1.5484 https://doaj.org/article/f8911171b25140a9af85b6b766020c1c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:f8911171b25140a9af85b6b766020c1c |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:f8911171b25140a9af85b6b766020c1c2021-12-02T17:18:43ZCOMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDYhttps://doi.org/10.51253/pafmj.v71iSuppl-1.54840030-96482411-8842https://doaj.org/article/f8911171b25140a9af85b6b766020c1c2021-01-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5484https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare lipid profile in patients with diabetic neuropathy and without neuropathy. Study Design: Cross-sectional comparative study. Place and Duration of Study: This study was carried out at Multidisciplinary Lab-1, Department of Biochemistry and Molecular Biology, Army Medical College, from Jan 2020 to Sep 2020 in collaboration with Pak-Emirates Military Hospital, Rawalpindi. Methodology: Eighty-four subjects were selected and divided into three groups, twenty-eight in each. Group I included diagnosed patients with type 2 diabetes mellitus with peripheral neuropathy, group II included diagnosed patients with type 2 diabetes mellitus without peripheral neuropathy and group III consisted of healthy individuals. Biochemical parameters including total cholesterol, triglycerides, high density lipoprotein cholesterol and low density lipoprotein cholesterol were measured. Data was analyzed by SPSS version 22.0. One way ANOVA test was used that followed by post-Hoc Tukey test for group comparison. Results: There was significant difference in triglycerides (p-value 0.001) and high density lipoprotein cholesterol (0.003) levels among group I and III. While, between group II and III significant difference of high density lipoprotein cholesterol was present. There was no significant difference between group I and II regarding all lipid profile parameters. Conclusion: There was significant increase of triglycerides levels and decrease of high density lipoprotein cholesterol in patients with diabetic peripheral neuropathy as compared to healthy controls. No significant difference was observed for all parameters of lipid profile between patients with diabetic peripheral neuropathy and without peripheral neuropathy.Kanwal HumaKhadija MehboobAmir RashidFatima FuadMuhammad Mamoon MujahidAsma ArshadArmy Medical College Rawalpindiarticlediabetic peripheral neuropathylipid profiletype 2 diabetes mellitusMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss SUPPL-1, Pp 202-206 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
diabetic peripheral neuropathy lipid profile type 2 diabetes mellitus Medicine R Medicine (General) R5-920 |
spellingShingle |
diabetic peripheral neuropathy lipid profile type 2 diabetes mellitus Medicine R Medicine (General) R5-920 Kanwal Huma Khadija Mehboob Amir Rashid Fatima Fuad Muhammad Mamoon Mujahid Asma Arshad COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY |
description |
Objective: To compare lipid profile in patients with diabetic neuropathy and without neuropathy.
Study Design: Cross-sectional comparative study.
Place and Duration of Study: This study was carried out at Multidisciplinary Lab-1, Department of Biochemistry and Molecular Biology, Army Medical College, from Jan 2020 to Sep 2020 in collaboration with Pak-Emirates Military Hospital, Rawalpindi.
Methodology: Eighty-four subjects were selected and divided into three groups, twenty-eight in each. Group I
included diagnosed patients with type 2 diabetes mellitus with peripheral neuropathy, group II included diagnosed patients with type 2 diabetes mellitus without peripheral neuropathy and group III consisted of healthy individuals. Biochemical parameters including total cholesterol, triglycerides, high density lipoprotein cholesterol and low density lipoprotein cholesterol were measured. Data was analyzed by SPSS version 22.0. One way ANOVA test was used that followed by post-Hoc Tukey test for group comparison.
Results: There was significant difference in triglycerides (p-value 0.001) and high density lipoprotein cholesterol
(0.003) levels among group I and III. While, between group II and III significant difference of high density lipoprotein cholesterol was present. There was no significant difference between group I and II regarding all lipid profile parameters.
Conclusion: There was significant increase of triglycerides levels and decrease of high density lipoprotein
cholesterol in patients with diabetic peripheral neuropathy as compared to healthy controls. No significant
difference was observed for all parameters of lipid profile between patients with diabetic peripheral neuropathy
and without peripheral neuropathy. |
format |
article |
author |
Kanwal Huma Khadija Mehboob Amir Rashid Fatima Fuad Muhammad Mamoon Mujahid Asma Arshad |
author_facet |
Kanwal Huma Khadija Mehboob Amir Rashid Fatima Fuad Muhammad Mamoon Mujahid Asma Arshad |
author_sort |
Kanwal Huma |
title |
COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY |
title_short |
COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY |
title_full |
COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY |
title_fullStr |
COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY |
title_full_unstemmed |
COMPARISON OF LIPID PROFILE IN PATIENTS WITH DIABETIC NEUROPATHY AND WITHOUT NEUROPATHY; A CROSS SECTIONAL STUDY |
title_sort |
comparison of lipid profile in patients with diabetic neuropathy and without neuropathy; a cross sectional study |
publisher |
Army Medical College Rawalpindi |
publishDate |
2021 |
url |
https://doi.org/10.51253/pafmj.v71iSuppl-1.5484 https://doaj.org/article/f8911171b25140a9af85b6b766020c1c |
work_keys_str_mv |
AT kanwalhuma comparisonoflipidprofileinpatientswithdiabeticneuropathyandwithoutneuropathyacrosssectionalstudy AT khadijamehboob comparisonoflipidprofileinpatientswithdiabeticneuropathyandwithoutneuropathyacrosssectionalstudy AT amirrashid comparisonoflipidprofileinpatientswithdiabeticneuropathyandwithoutneuropathyacrosssectionalstudy AT fatimafuad comparisonoflipidprofileinpatientswithdiabeticneuropathyandwithoutneuropathyacrosssectionalstudy AT muhammadmamoonmujahid comparisonoflipidprofileinpatientswithdiabeticneuropathyandwithoutneuropathyacrosssectionalstudy AT asmaarshad comparisonoflipidprofileinpatientswithdiabeticneuropathyandwithoutneuropathyacrosssectionalstudy |
_version_ |
1718381121099530240 |