The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors

The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors

The chemokine receptor CXCR3-A is expressed in high grade glioma. Here the authors show that CXCR3-A interacts with LPR1, a protein highly expressed in glioma, and this interaction regulates the trafficking of the receptor ultimately impacting on tumour cell migration.

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Autores principales: Kevin Boyé, Nadège Pujol, Isabel D Alves, Ya-Ping Chen, Thomas Daubon, Yi-Zong Lee, Stephane Dedieu, Marion Constantin, Lorenzo Bello, Marco Rossi, Rolf Bjerkvig, Shih-Che Sue, Andreas Bikfalvi, Clotilde Billottet
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f89aab30d6554471bcccc005f3a1f7b0
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spelling oai:doaj.org-article:f89aab30d6554471bcccc005f3a1f7b02021-12-02T14:42:23ZThe role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors10.1038/s41467-017-01686-y2041-1723https://doaj.org/article/f89aab30d6554471bcccc005f3a1f7b02017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01686-yhttps://doaj.org/toc/2041-1723The chemokine receptor CXCR3-A is expressed in high grade glioma. Here the authors show that CXCR3-A interacts with LPR1, a protein highly expressed in glioma, and this interaction regulates the trafficking of the receptor ultimately impacting on tumour cell migration.Kevin BoyéNadège PujolIsabel D AlvesYa-Ping ChenThomas DaubonYi-Zong LeeStephane DedieuMarion ConstantinLorenzo BelloMarco RossiRolf BjerkvigShih-Che SueAndreas BikfalviClotilde BillottetNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-20 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kevin Boyé
Nadège Pujol
Isabel D Alves
Ya-Ping Chen
Thomas Daubon
Yi-Zong Lee
Stephane Dedieu
Marion Constantin
Lorenzo Bello
Marco Rossi
Rolf Bjerkvig
Shih-Che Sue
Andreas Bikfalvi
Clotilde Billottet
The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors
description The chemokine receptor CXCR3-A is expressed in high grade glioma. Here the authors show that CXCR3-A interacts with LPR1, a protein highly expressed in glioma, and this interaction regulates the trafficking of the receptor ultimately impacting on tumour cell migration.
format article
author Kevin Boyé
Nadège Pujol
Isabel D Alves
Ya-Ping Chen
Thomas Daubon
Yi-Zong Lee
Stephane Dedieu
Marion Constantin
Lorenzo Bello
Marco Rossi
Rolf Bjerkvig
Shih-Che Sue
Andreas Bikfalvi
Clotilde Billottet
author_facet Kevin Boyé
Nadège Pujol
Isabel D Alves
Ya-Ping Chen
Thomas Daubon
Yi-Zong Lee
Stephane Dedieu
Marion Constantin
Lorenzo Bello
Marco Rossi
Rolf Bjerkvig
Shih-Che Sue
Andreas Bikfalvi
Clotilde Billottet
author_sort Kevin Boyé
title The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors
title_short The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors
title_full The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors
title_fullStr The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors
title_full_unstemmed The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors
title_sort role of cxcr3/lrp1 cross-talk in the invasion of primary brain tumors
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/f89aab30d6554471bcccc005f3a1f7b0
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