Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis

Myasthenia is a chronic autoimmune neuromuscular disease. Antibodies to acetylcholine receptors are found in 85-90 % of patients with generalized myasthenia and play an important role in the pathogenesis of the disease. In the article compared comparison of the level of antibodies to the acetylcholi...

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Autor principal:	T. V. Romanova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	myasthenia gravis antibodies to acetylcholine receptors immune-enzymatic method Science Q
Acceso en línea:	https://doaj.org/article/f8a779df870e438c926da02017736d75
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spelling	oai:doaj.org-article:f8a779df870e438c926da02017736d752021-11-23T06:14:27ZResearch of antibodies to the acetylcholine receptors in patients with myasthenia gravis2541-94202587-9596https://doaj.org/article/f8a779df870e438c926da02017736d752013-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1532https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Myasthenia is a chronic autoimmune neuromuscular disease. Antibodies to acetylcholine receptors are found in 85-90 % of patients with generalized myasthenia and play an important role in the pathogenesis of the disease. In the article compared comparison of the level of antibodies to the acetylcholine receptors (AChR) in patients with myasthenia gravis with the severity and duration of disease, age of onset, changes in the thymus and. treatment was realized. We examined. 80 patients. The research of antibodies was conducted by immune-enzymatic method. The highest levels of antibodies to AChR were detected in the group of patients who received long-term cytotoxic agents due to the steady progress of the disease. High. level of antibodies to AChR was observed in patients with predominance of weakness in craniobulbar muscles in clinical presentation. There were no correlations of level of antibodies to AChR with sex, duration of disease, presence of thymoma.T. V. RomanovaScientific Сentre for Family Health and Human Reproduction Problemsarticlemyasthenia gravisantibodies to acetylcholine receptorsimmune-enzymatic methodScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(1), Pp 82-86 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	myasthenia gravis antibodies to acetylcholine receptors immune-enzymatic method Science Q
spellingShingle	myasthenia gravis antibodies to acetylcholine receptors immune-enzymatic method Science Q T. V. Romanova Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis
description	Myasthenia is a chronic autoimmune neuromuscular disease. Antibodies to acetylcholine receptors are found in 85-90 % of patients with generalized myasthenia and play an important role in the pathogenesis of the disease. In the article compared comparison of the level of antibodies to the acetylcholine receptors (AChR) in patients with myasthenia gravis with the severity and duration of disease, age of onset, changes in the thymus and. treatment was realized. We examined. 80 patients. The research of antibodies was conducted by immune-enzymatic method. The highest levels of antibodies to AChR were detected in the group of patients who received long-term cytotoxic agents due to the steady progress of the disease. High. level of antibodies to AChR was observed in patients with predominance of weakness in craniobulbar muscles in clinical presentation. There were no correlations of level of antibodies to AChR with sex, duration of disease, presence of thymoma.
format	article
author	T. V. Romanova
author_facet	T. V. Romanova
author_sort	T. V. Romanova
title	Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis
title_short	Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis
title_full	Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis
title_fullStr	Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis
title_full_unstemmed	Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis
title_sort	research of antibodies to the acetylcholine receptors in patients with myasthenia gravis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/f8a779df870e438c926da02017736d75
work_keys_str_mv	AT tvromanova researchofantibodiestotheacetylcholinereceptorsinpatientswithmyastheniagravis
_version_	1718417171042795520

Research of antibodies to the acetylcholine receptors in patients with myasthenia gravis

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