Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty

Risk of age-related chronic disorders and decrease in resilience is associated with ageing. Here the authors analyse the human blood metabolome and identify metabolites associated with frailty.

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Autores principales:	Nicholas J. W. Rattray, Drupad K. Trivedi, Yun Xu, Tarani Chandola, Caroline H. Johnson, Alan D. Marshall, Krisztina Mekli, Zahra Rattray, Gindo Tampubolon, Bram Vanhoutte, Iain R. White, Frederick C. W. Wu, Neil Pendleton, James Nazroo, Royston Goodacre
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f8a8be46f83b45fc975dd3c54a72ffd7
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spelling	oai:doaj.org-article:f8a8be46f83b45fc975dd3c54a72ffd72021-12-02T15:36:22ZMetabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty10.1038/s41467-019-12716-22041-1723https://doaj.org/article/f8a8be46f83b45fc975dd3c54a72ffd72019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12716-2https://doaj.org/toc/2041-1723Risk of age-related chronic disorders and decrease in resilience is associated with ageing. Here the authors analyse the human blood metabolome and identify metabolites associated with frailty.Nicholas J. W. RattrayDrupad K. TrivediYun XuTarani ChandolaCaroline H. JohnsonAlan D. MarshallKrisztina MekliZahra RattrayGindo TampubolonBram VanhoutteIain R. WhiteFrederick C. W. WuNeil PendletonJames NazrooRoyston GoodacreNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicholas J. W. Rattray Drupad K. Trivedi Yun Xu Tarani Chandola Caroline H. Johnson Alan D. Marshall Krisztina Mekli Zahra Rattray Gindo Tampubolon Bram Vanhoutte Iain R. White Frederick C. W. Wu Neil Pendleton James Nazroo Royston Goodacre Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
description	Risk of age-related chronic disorders and decrease in resilience is associated with ageing. Here the authors analyse the human blood metabolome and identify metabolites associated with frailty.
format	article
author	Nicholas J. W. Rattray Drupad K. Trivedi Yun Xu Tarani Chandola Caroline H. Johnson Alan D. Marshall Krisztina Mekli Zahra Rattray Gindo Tampubolon Bram Vanhoutte Iain R. White Frederick C. W. Wu Neil Pendleton James Nazroo Royston Goodacre
author_facet	Nicholas J. W. Rattray Drupad K. Trivedi Yun Xu Tarani Chandola Caroline H. Johnson Alan D. Marshall Krisztina Mekli Zahra Rattray Gindo Tampubolon Bram Vanhoutte Iain R. White Frederick C. W. Wu Neil Pendleton James Nazroo Royston Goodacre
author_sort	Nicholas J. W. Rattray
title	Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
title_short	Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
title_full	Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
title_fullStr	Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
title_full_unstemmed	Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
title_sort	metabolic dysregulation in vitamin e and carnitine shuttle energy mechanisms associate with human frailty
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f8a8be46f83b45fc975dd3c54a72ffd7
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Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty

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