Exosome-associated host–pathogen interaction: a potential effect of biofilm formation

Abstract Exosomes being non-ionized micro-vesicles with a size range of 30–100 nm possess the ability to bring about intracellular communication and intercellular transport of various types of cellular components like miRNA, mRNA, DNA, and proteins. This is achieved through the targeted transmission...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Dibyajit Lahiri, Moupriya Nag, Ankita Dey, Tanmay Sarkar, Smaranika Pattnaik, Sougata Ghosh, Hisham Atan Edinur, Siddhartha Pati, Zulhisyam Abdul Kari, Rina Rani Ray
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Exosomes Membrane vesicles Immunogenic response Biofilm Resistance Bioprospecting Chemistry QD1-999 Analytical chemistry QD71-142
Acceso en línea:	https://doaj.org/article/f8c1e7ec0857405680f062ea231490a5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f8c1e7ec0857405680f062ea231490a5
record_format	dspace
spelling	oai:doaj.org-article:f8c1e7ec0857405680f062ea231490a52021-11-14T12:07:51ZExosome-associated host–pathogen interaction: a potential effect of biofilm formation10.1186/s40543-021-00306-12093-3371https://doaj.org/article/f8c1e7ec0857405680f062ea231490a52021-11-01T00:00:00Zhttps://doi.org/10.1186/s40543-021-00306-1https://doaj.org/toc/2093-3371Abstract Exosomes being non-ionized micro-vesicles with a size range of 30–100 nm possess the ability to bring about intracellular communication and intercellular transport of various types of cellular components like miRNA, mRNA, DNA, and proteins. This is achieved through the targeted transmission of various inclusions to nearby or distant tissues. This is associated with the effective communication of information to bring about changes in physiological properties and functional attributes. The extracellular vesicles (EVs), produced by fungi, parasites, and bacteria, are responsible to bring about modulation/alteration of the immune responses exerted by the host body. The lipids, nucleic acids, proteins, and glycans of EVs derived from the pathogens act as the ligands of different families of pattern recognition receptors of the host body. The bacterial membrane vesicles (BMVs) are responsible for the transfer of small RNA species, along with other types of noncoding RNA thereby playing a key role in the regulation of the host immune system. Apart from immunomodulation, the BMVs are also responsible for bacterial colonization in the host tissue, biofilm formation, and survival therein showing antibiotic resistance, leading to pathogenesis and virulence. This mini-review would focus on the role of exosomes in the development of biofilm and consequent immunological responses within the host body along with an analysis of the mechanism associated with the development of resistance.Dibyajit LahiriMoupriya NagAnkita DeyTanmay SarkarSmaranika PattnaikSougata GhoshHisham Atan EdinurSiddhartha PatiZulhisyam Abdul KariRina Rani RaySpringerOpenarticleExosomesMembrane vesiclesImmunogenic responseBiofilmResistanceBioprospectingChemistryQD1-999Analytical chemistryQD71-142ENJournal of Analytical Science and Technology, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Exosomes Membrane vesicles Immunogenic response Biofilm Resistance Bioprospecting Chemistry QD1-999 Analytical chemistry QD71-142
spellingShingle	Exosomes Membrane vesicles Immunogenic response Biofilm Resistance Bioprospecting Chemistry QD1-999 Analytical chemistry QD71-142 Dibyajit Lahiri Moupriya Nag Ankita Dey Tanmay Sarkar Smaranika Pattnaik Sougata Ghosh Hisham Atan Edinur Siddhartha Pati Zulhisyam Abdul Kari Rina Rani Ray Exosome-associated host–pathogen interaction: a potential effect of biofilm formation
description	Abstract Exosomes being non-ionized micro-vesicles with a size range of 30–100 nm possess the ability to bring about intracellular communication and intercellular transport of various types of cellular components like miRNA, mRNA, DNA, and proteins. This is achieved through the targeted transmission of various inclusions to nearby or distant tissues. This is associated with the effective communication of information to bring about changes in physiological properties and functional attributes. The extracellular vesicles (EVs), produced by fungi, parasites, and bacteria, are responsible to bring about modulation/alteration of the immune responses exerted by the host body. The lipids, nucleic acids, proteins, and glycans of EVs derived from the pathogens act as the ligands of different families of pattern recognition receptors of the host body. The bacterial membrane vesicles (BMVs) are responsible for the transfer of small RNA species, along with other types of noncoding RNA thereby playing a key role in the regulation of the host immune system. Apart from immunomodulation, the BMVs are also responsible for bacterial colonization in the host tissue, biofilm formation, and survival therein showing antibiotic resistance, leading to pathogenesis and virulence. This mini-review would focus on the role of exosomes in the development of biofilm and consequent immunological responses within the host body along with an analysis of the mechanism associated with the development of resistance.
format	article
author	Dibyajit Lahiri Moupriya Nag Ankita Dey Tanmay Sarkar Smaranika Pattnaik Sougata Ghosh Hisham Atan Edinur Siddhartha Pati Zulhisyam Abdul Kari Rina Rani Ray
author_facet	Dibyajit Lahiri Moupriya Nag Ankita Dey Tanmay Sarkar Smaranika Pattnaik Sougata Ghosh Hisham Atan Edinur Siddhartha Pati Zulhisyam Abdul Kari Rina Rani Ray
author_sort	Dibyajit Lahiri
title	Exosome-associated host–pathogen interaction: a potential effect of biofilm formation
title_short	Exosome-associated host–pathogen interaction: a potential effect of biofilm formation
title_full	Exosome-associated host–pathogen interaction: a potential effect of biofilm formation
title_fullStr	Exosome-associated host–pathogen interaction: a potential effect of biofilm formation
title_full_unstemmed	Exosome-associated host–pathogen interaction: a potential effect of biofilm formation
title_sort	exosome-associated host–pathogen interaction: a potential effect of biofilm formation
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/f8c1e7ec0857405680f062ea231490a5
work_keys_str_mv	AT dibyajitlahiri exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT moupriyanag exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT ankitadey exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT tanmaysarkar exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT smaranikapattnaik exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT sougataghosh exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT hishamatanedinur exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT siddharthapati exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT zulhisyamabdulkari exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation AT rinaraniray exosomeassociatedhostpathogeninteractionapotentialeffectofbiofilmformation
_version_	1718429443021602816

Exosome-associated host–pathogen interaction: a potential effect of biofilm formation

Ejemplares similares